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Phorbol 12,13-dibutyrate

Tocris Bioscience a Bio-Techne Brand

Phorbol 12,13-dibutyrate | CAS No. 37558-16-0 | Protein kinase C activator
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Key Product Details

Description: Protein kinase C activator
Alternative Names: PDBu
Chemical Name: (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-1a,1b,4,4a,5,7a,7b,8,9,9a-Decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1H-cyclopropa[3,4]benz[1,2-e]azulen-9,9a-diyl butanoic acid ester
Purity: ≥97% (HPLC)
Molecular Weight: 504.61

Citations for Phorbol 12,13-dibutyrate (3)

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  • PDB reduces saxagliptin-induced APD prolongation in cardiomyocytes
    Name: Chintan Koyani
    Species: Other
    Assay Type: In Vitro
    Cell Line/Tissue: ventricular cardiomyocytes
    Guinea pig ventricular cardiomyocytes were patched and superfused with Saxagliptin (2 µM, 5 min) followed by Phorbol 12,13-dibutyrate (PDB, 10 nM, 5 min) and action potentials were stimulated at a 1 Hz frequency. Action potential duration (APD) were analysed at 20%, 50% and 90% repolarization (shown in Image). PDB reduced saxagliptin-induced APD prolongation.
    Phorbol 12,13-dibutyrate Serum 4153

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Product Documents for Phorbol 12,13-dibutyrate

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