Pertussis Toxin

Citations are publications that use Bio-Techne products. Selected citations for Pertussis Toxin include:

• Wyant et al. (2022) Mitochondrial remodeling and ischemic protection by G protein�coupled receptor 35 agonists. Science. 377:621
  PMID: 35926043
• Hu et al. (2022) Epigenetic drug screen identified IOX1 as an inhibitor of Th17-mediated inflammation through targeting TET2. EBioMedicine. 86:104333
  PMID: 36335665
• Nepomuceno et al. (2018) Re-evaluation of Adrenocorticotropic Hormone and Melanocyte Stimulating Hormone Activation of GPR139 in Vitro. Front Pharmacol. 9:157
  PMID: 29599718
• Zhao et al. (2018) Ethanolic Extract of Folium Sennae Mediates the Glucose Uptake of L6 Cells by GLUT4 and Ca2. Molecules. 23
  PMID: 30424024
• O'Neill & Sylantyev (2018) Selective modulation of tonically active GABA_A receptor functional subgroups by G-proteins and protein kinase C. Exp Biol Med (Maywood). 243:1046
  PMID: 30205722
• Li et al. (2017) Follicular Stimulating Hormone Accelerates Atherogenesis by Increasing Endothelial VCAM-1 Expression. Theranostics. 7:4671
  PMID: 29187895
• Yuan et al. (2016) Ciliary IFT80 balances canonical versus non-canonical hedgehog signalling for osteoblast differentiation. Am J Physiol Heart Circ Physiol. 7:11024
  PMID: 26996322
• Jones et al. (2015) Pathogenic aquaporin-4 reactive T cells are sufficient to induce mouse model of neuromyelitis optica. Acta Neuropathol Commun. 3:28
  PMID: 25990016
• Stott et al. (2015) G-protein βγ subunits are positive regulators of Kv7.4 and native vascular Kv7 channel activity. Dis Model Mech. 112:6497
  PMID: 25941381
• Sim et al. (2015) A simple method for in vivo labelling of infiltrating leukocytes in the mouse retina using indocy. green dye. Int J Cancer. 8:1479
  PMID: 26398933
• Choi et al. (2015) SDF-1α stiffens myeloma bone marrow mesenchymal stromal cells through the activation of RhoA-ROCK-Myosin II. J Neurosci. 136:E219
  PMID: 25137150
• Crawford et al. (2015) The role of lipoprotein-associated phospholipase A2 in a murine model of experimental autoimmune uveoretinitis. PLoS One. 10:e0122093
  PMID: 25874928
• Boldison et al. (2014) Tissue-resident exhausted effector memory CD8+ T cells accumulate in the retina during chronic experimental autoimmune uveoretinitis. J Immunol. 192:4541
  PMID: 24740509
• Butschkau et al. (2014) Protein z exerts pro-angiogenic effects and upregulates CXCR4. PLoS One. 9:e113554
  PMID: 25474349
• Rimmerman et al. (2013) Direct modulation of the outer mitochondrial membrane channel, voltage-dependent anion channel 1 (VDAC1) by cannabidiol: a novel mechanism for cannabinoid-induced cell death. Cell Death Dis. 4:e949
  PMID: 24309936
• Wydeven et al. (2012) Structural elements in the Girk1 subunit that potentiate G protein-gated potassium channel activity. Proc Natl Acad Sci U S A. 109:21492
  PMID: 23236146
• Cheng et al. (2012) Cytoskeletal role in protection of the failing heart by β-adrenergic blockade. Proc Natl Acad Sci U S A. 302:H675
  PMID: 22081703
• Meitzen et al. (2011) β1-Adrenergic receptors activate two distinct signaling pathways in striatal neurons. J Neurochem. 116:984
  PMID: 21143600
• Park et al. (2011) Resolvin D2 is a potent endogenous inhibitor for transient receptor potential subtype V1/A1, inflammatory pain, and spinal cord synaptic plasticity in mice: distinct roles of resolvin D1, D2, and E1. Neuron. 31:18433
  PMID: 22171045
• Schutsky et al. (2011) Stress and glucocorticoids impair memory retrieval via β2-adrenergic, Gi/o-coupled suppression of cAMP signaling. J Neurosci. 31:14172
  PMID: 21976502
• Nagaraja et al. (1999) Treatment with inverse agonists enhances baseline atrial contractility in transgenic mice with chronic β2-adrenoceptor activation. Nat Commun. 127:1099
  PMID: 10455254

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• Pertussis toxin impacts GABA-A receptor effects

  Name: Anonymous
  Species: Rat
  Assay Type: In Vitro
  Pertussis toxin (PeTX) was used to compare effects of PKA and G-protein signalling on root mean square noise (RMS) produced by GABA-A receptors in electrophysiological recording. We found that after block of G-protein signalling with PeTX GABA-A receptor antagonists SR 95531 and Picrotoxin generate smaller impact on RMS noise than after block of PKA with PKI.
  PMID: 30205722
  

• Pertussis Toxin inhibits LPA induced COX-2 expression in osteosarcoma cells

  Name: Christopher Trummer
  Species: Human
  Assay Type: In Vitro
  Cell Line/Tissue: Osteosarcoma
  MG-63 cells were treated with LPA (10 µM) alone or in combination with C3 (20 µM), PTX (Pertussis Toxin, 400 ng/ml) or H2L 5765834 (20 µM) for 3 h to follow COX-2 expression using Western blot. Pertussis Toxin inhibited COX-2 expression induced by LPA.
  

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