Pan Caspase OPH Inhibitor Q-VD, Non-omethylated
R&D Systems, Inc. a Bio-Techne Brand
Key Product Details
Citations for Pan Caspase OPH Inhibitor Q-VD, Non-omethylated (36)
Citations are publications that use Bio-Techne products. Selected citations for Pan Caspase OPH Inhibitor Q-VD, Non-omethylated include:
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Species: Human
Sample Types: Whole Cells
MT Gomes et al. (2022), Phosphatidylserine externalization by apoptotic cells is dispensable for specific recognition leading to innate apoptotic immune responses The Journal of Biological Chemistry, 0(0):102034.
PMID: 35588784 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayF Bai et al. (2022), Wogonin attenuates neutrophilic inflammation and airway smooth muscle proliferation through inducing caspase-dependent apoptosis and inhibiting MAPK/Akt signaling in allergic airways International immunopharmacology, 113(0):109410.
PMID: 36371864 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayM Samuel et al. (2021), Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Nature Communications, 12(1):3950.
PMID: 34168137 -
S Núñez-Vázq et al. (2021), The prohibitin-binding compound fluorizoline inhibits mitophagy in cancer cells Oncogenesis, 10(9):64.
PMID: 34580273 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayA Kratochvil et al. (2021), Impact of FasL Stimulation on Sclerostin Expression and Osteogenic Profile in IDG-SW3 Osteocytes Biology, 10(8).
PMID: 34439989 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayTA Giovannucc et al. (2021), Inhibition of the ubiquitin-proteasome system by an NQO1-activatable compound Cell Death Disease, 2021;12(10):914.
PMID: 34615851 -
MA Miles et al. (2020), In vitro analysis reveals necroptotic signaling does not provoke DNA damage or HPRT mutations Cell Death Dis, 11(8):680.
PMID: 32826875 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA Di Grazia et al. (2020), The Fragile X Mental Retardation Protein regulates RIP1K and colorectal cancer resistance to necroptosis Cell Mol Gastroenterol Hepatol, 0(0).
PMID: 33091622 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMA Miles et al. (2020), In vitro analysis reveals necroptotic signaling does not provoke DNA damage or HPRT mutations Cell Death Dis, 11(8):680.
PMID: 32826875 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKW Chen et al. (2018), Cutting Edge: Blockade of Inhibitor of Apoptosis Proteins Sensitizes Neutrophils to TNF- but Not Lipopolysaccharide-Mediated Cell Death and IL-1? Secretion J. Immunol., 0(0).
PMID: 29661823 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA de Las Poz et al. (2018), Inhibiting Multiple Deubiquitinases to Reduce Androgen Receptor Expression in Prostate Cancer Cells Sci Rep, 8(1):13146.
PMID: 30177856 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySA Conos et al. (2017), Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner Proc. Natl. Acad. Sci. U.S.A, 0(0).
PMID: 28096356 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMA Miles et al. (2017), Executioner caspases and CAD are essential for mutagenesis induced by TRAIL or vincristine Cell Death Dis, 8(10):e3062.
PMID: 28981092 -
Species: Avian - Coturnix coturnix japonica (Quail)
Sample Types: Whole Tissue
Applications: BioassayM Martín-Est et al. (2017), Onset of microglial entry into developing quail retina coincides with increased expression of active caspase-3 and is mediated by extracellular ATP and UDP PLoS ONE, 12(8):e0182450.
PMID: 28763502 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayE Schmukler et al. (2017), Continuous treatment with FTS confers resistance to apoptosis and affects autophagy PLoS ONE, 12(2):e0171351.
PMID: 28151959 -
Species: Human
Sample Types: Whole Cells
Cortes C et al. (2016), Effect of low doses of actinomycin D on neuroblastoma cell lines. Mol Cancer, 15(1):1.
PMID: 26728659 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLaine A et al. (2015), Foxo1 Is a T Cell-Intrinsic Inhibitor of the RORgammat-Th17 Program. J Immunol, 195(4):1791-803.
PMID: 26170390 -
Species: Rat
Sample Types: Whole Cells
Bahrini et al. (2015), Neuronal exosomes facilitate synaptic pruning by up-regulating complement factors in microglia. Sci Rep, 5(0):7989.
PMID: 25612542 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayTebbi A et al. (2015), Caspase-dependent Proteolysis of Human Ribonucleotide Reductase Small Subunits R2 and p53R2 during Apoptosis. J Biol Chem, 290(22):14077-90.
PMID: 25878246 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLawlor K et al. (2015), RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL. Nat Commun, 6(0):6282.
PMID: 25693118 -
Species: Human
Sample Types: Whole Cells
Liu Y et al. (2015), CHCHD2 inhibits apoptosis by interacting with Bcl-x L to regulate Bax activation. Cell Death Differ, 22(6):1035-46.
PMID: 25476776 -
Lucas et al. (2014), Downregulation of Mcl-1 has anti-inflammatory pro-resolution effects and enhances bacterial clearance from the lung. Mucosal Immunol, 7(4):857-68.
PMID: 24280938 -
Species: Human
Sample Types: Cell Lysates
Valenzuela M et al. (2014), Retinoic acid synergizes ATO-mediated cytotoxicity by precluding Nrf2 activity in AML cells. Br J Cancer, 111(5):874-82.
PMID: 25003661 -
Greenlee-Wacker M et al. (2014), Phagocytosis of Staphylococcus aureus by human neutrophils prevents macrophage efferocytosis and induces programmed necrosis. J Immunol, 192(10):4709-17.
PMID: 24729616 -
Species: Mouse
Sample Types: Whole Cells
Baracho G et al. (2014), PDK1 regulates B cell differentiation and homeostasis. Proc Natl Acad Sci U S A, 111(26):9573-8.
PMID: 24979759 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayEl-Khoury V et al. (2014), Disruption of autophagy by the histone deacetylase inhibitor MGCD0103 and its therapeutic implication in B-cell chronic lymphocytic leukemia. Leukemia, 28(8):1636-46.
PMID: 24418989 -
Galan-Moya E et al. (2014), Endothelial secreted factors suppress mitogen deprivation-induced autophagy and apoptosis in glioblastoma stem-like cells. PLoS ONE, 9(3):e93505.
PMID: 24682219 -
Species: Mouse
Sample Types: Whole Cells
Yamaguchi et al. (2014), Immunosuppression via adenosine receptor activation by adenosine monophosphate released from apoptotic cells. Elife, 3(0):e02172.
PMID: 24668173 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMurphy J et al. (2013), The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism. Immunity, 39(3):443-53.
PMID: 24012422 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayColacurcio D et al. (2013), Calpain-mediated degradation of MDMx/MDM4 contributes to HIV-induced neuronal damage. Mol Cell Neurosci, 57(0):54-62.
PMID: 24128662 -
Suzuki et al. (2013), Calcium-dependent phospholipid scramblase activity of TMEM16 protein family members. J Biol Chem, 288(19):13305-16.
PMID: 23532839 -
Bertin-Ciftci J et al. (2013), pRb/E2F-1-mediated caspase-dependent induction of Noxa amplifies the apoptotic effects of the Bcl-2/Bcl-xL inhibitor ABT-737. Cell Death Differ, 20(5):755-64.
PMID: 23429261 -
Species: Human
Sample Types: Whole Cells
Jak M et al. (2011), CD40 stimulation sensitizes CLL cells to lysosomal cell death induction by type II anti-CD20 mAb GA101. Blood, 118(19):5178-88.
PMID: 21948297 -
Species: Human
Sample Types: Whole Cells
Jones JL et al. (2009), IL-21 drives secondary autoimmunity in patients with multiple sclerosis, following therapeutic lymphocyte depletion with alemtuzumab (Campath-1H). J. Clin. Invest., 119(7):2052-61.
PMID: 19546505 -
Species: Mouse
Sample Types: Whole Cells
Son KN et al. (2008), Theiler's virus-induced intrinsic apoptosis in M1-D macrophages is Bax mediated and restricts virus infectivity: a mechanism for persistence of a cytolytic virus. J. Virol., 82(9):4502-10.
PMID: 18287228 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayPetit I et al. (2007), The microtubule-targeting agent CA4P regresses leukemic xenografts by disrupting interaction with vascular cells and mitochondrial-dependent cell death. Blood, 111(4):1951-61.
PMID: 18024794
There are no citations that match your criteria.
FAQs for Pan Caspase OPH Inhibitor Q-VD, Non-omethylated
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Are R&D Systems Caspase Inhibitors irreversible?
Yes, the majority of R&D Systems Caspase Inhibitors have a Fluoromethyl ketone (FMK) functional group on the C-terminus of the peptide, and act as effective irreversible inhibitors with no added cytotoxic effects. Inhibitors synthesized with a benzyloxycarbonyl group (also known as BOC or Z) at the N-terminus and O-methyl side chains exhibit enhanced cellular permeability.R&D Systems also offers a General Caspase Inhibitor, Q-VD-OPh, Catalog # OPH001, as well as a FITC-conjugated pan-caspase inhibitor (ApoStat), Catalog # FMK012, which are both cell-permeable, irreversible inhibitors of caspase activity.