Pan Caspase Inhibitor Z-VAD-FMK

Citations are publications that use Bio-Techne products. Selected citations for Pan Caspase Inhibitor Z-VAD-FMK include:

• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  M Glumac et al. (2023), Mechanism of cis-Nerolidol-Induced Bladder Carcinoma Cell Death Cancers, 15(3).
  PMID:  36765938
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  CDB Gamage et al. (2023), Libertellenone T, a Novel Compound Isolated from Endolichenic Fungus, Induces G2/M Phase Arrest, Apoptosis, and Autophagy by Activating the ROS/JNK Pathway in Colorectal Cancer Cells Cancers, 15(2).
  PMID:  36672439
• Species: Mouse
  Sample Types: Whole Cells
  Applications: Bioassay

  B Lee et al. (2022), FK506-binding protein-like and FK506-binding protein 8 regulate dual leucine zipper kinase degradation and neuronal responses to axon injury The Journal of Biological Chemistry, 0(0):101647.
  PMID:  35101451
• Species: Human
  Sample Types: Recombinant Proteins
  Applications: Bioassay

  W Deng et al. (2022), Streptococcal pyrogenic exotoxin B cleaves GSDMA and triggers pyroptosis Nature, 0(0).
  PMID:  35110732
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  D Beillevair et al. (2022), Autolysosomes and caspase-3 control the biogenesis and release of immunogenic apoptotic exosomes Cell Death Disease, 2022;13(2):145.
  PMID:  35149669
• Species: Mouse
  Sample Types: Whole Cells
  Applications: Bioassay

  CR Bell et al. (2022), Chemotherapy-induced COX-2 upregulation by cancer cells defines their inflammatory properties and limits the efficacy of chemoimmunotherapy combinations Nature Communications, 13(1):2063.
  PMID:  35440553
• Species: Human
  Sample Types: Whole Cells
  Applications: Cell Culture

  N Landi et al. (2022), Isolation, Characterization and Biological Action of Type-1 Ribosome-Inactivating Proteins from Tissues of Salsola soda L Toxins, 14(8).
  PMID:  36006228
• Species: Human
  Sample Types: Whole Cells
  

  YS Michaels et al. (2022), DLL4 and VCAM1 enhance the emergence of T cell-competent hematopoietic progenitors from human pluripotent stem cells Science Advances, 8(34):eabn5522.
  PMID:  36001668
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  J Yang et al. (2022), Magmas Inhibition in Prostate Cancer: A Novel Target for Treatment-Resistant Disease Cancers, 14(11).
  PMID:  35681713
• Species: Human
  Sample Types: Whole Cells
  

  JH Kim et al. (2022), Vitamin C Suppresses Pancreatic Carcinogenesis through the Inhibition of Both Glucose Metabolism and Wnt Signaling International Journal of Molecular Sciences, 23(20).
  PMID:  36293106
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  SM Woo et al. (2022), Inhibition of USP1 enhances anticancer drugs-induced cancer cell death through downregulation of survivin and miR-216a-5p-mediated upregulation of DR5 Cell Death Disease, 2022;13(9):821.
  PMID:  36153316
• Species: Mouse
  Sample Types: Cell Culture Supernates
  Applications: Bioassay

  G Lee et al. (2022), JC2-11, a benzylideneacetophenone derivative, attenuates inflammasome activation Scientific Reports, 12(1):22484.
  PMID:  36577816
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  K Ibraheem et al. (2022), TRAF3/p38-JNK Signalling Crosstalk with Intracellular-TRAIL/Caspase-10-Induced Apoptosis Accelerates ROS-Driven Cancer Cell-Specific Death by CD40 Cells, 11(20).
  PMID:  36291141
• Species: Human
  Sample Types: Transfected Whole Cells
  Applications: Bioassay

  L Tilokani et al. (2022), AMPK-dependent phosphorylation of MTFR1L regulates mitochondrial morphology Science Advances, 8(45):eabo7956.
  PMID:  36367943
• Species: Rat
  Sample Types: Whole Cells
  Applications: Bioassay

  G Chen et al. (2021), Netrin-1 receptor UNC5C cleavage by active &delta-secretase enhances neurodegeneration, promoting Alzheimer's disease pathologies Science Advances, 7(16).
  PMID:  33863723
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  Y Li et al. (2021), Selective Anti-Cancer Effects of Plasma-Activated Medium and Its High Efficacy with Cisplatin on Hepatocellular Carcinoma with Cancer Stem Cell Characteristics International Journal of Molecular Sciences, 22(8).
  PMID:  33921230
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  G Xie et al. (2021), Characterization of HIV-induced remodeling reveals differences in infection susceptibility of memory CD4+ T�cell subsets in�vivo Cell Reports, 35(4):109038.
  PMID:  33910003
• Species: Mouse
  Sample Types: Whole Cells
  Applications: Bioassay

  K Woo et al. (2021), N-3-Hydroxy Dodecanoyl-DL-homoserine Lactone (OH-dDHL) Triggers Apoptosis of Bone Marrow-Derived Macrophages through the ER- and Mitochondria-Mediated Pathways International Journal of Molecular Sciences, 22(14).
  PMID:  34299184
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  DC Kanellis et al. (2021), The exon-junction complex helicase eIF4A3 controls cell fate via coordinated regulation of ribosome biogenesis and translational output Science Advances, 7(32).
  PMID:  34348895
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  MS Jeong et al. (2021), Synergistic Antitumor Activity of SH003 and Docetaxel via EGFR Signaling Inhibition in Non-Small Cell Lung Cancer International Journal of Molecular Sciences, 22(16).
  PMID:  34445110
• Species: Human
  Sample Types: Whole Cell
  Applications: Bioassay

  P Van Damme (2021), Charting the N-Terminal Acetylome: A Comprehensive Map of Human NatA Substrates International Journal of Molecular Sciences, 22(19).
  PMID:  34639033
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  R Cheng et al. (2021), ABT?737, a Bcl?2 family inhibitor, has a synergistic effect with apoptosis by inducing urothelial carcinoma cell necroptosis Molecular Medicine Reports, 23(6).
  PMID:  33786632
• Species: Mouse
  Sample Types: In Vivo
  Applications: In Vivo

  M Tsubota et al. (2021), Caspase-Dependent HMGB1 Release from Macrophages Participates in Peripheral Neuropathy Caused by Bortezomib, a Proteasome-Inhibiting Chemotherapeutic Agent, in Mice Cells, 10(10).
  PMID:  34685531
• Species: Mouse
  Sample Types: Whole Cells
  Applications: Bioassay

  JL Cannons et al. (2021), PI3Kdelta coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T�cells at the expense of central memory Cell Reports, 37(2):109804.
  PMID:  34644563
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  C Mao et al. (2021), DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer Nature, 0(0).
  PMID:  33981038
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  K Wu et al. (2021), Inhibition of BMI-1 Induces Apoptosis through Downregulation of DUB3-Mediated Mcl-1 Stabilization International Journal of Molecular Sciences, 22(18).
  PMID:  34576269
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  TW Kim et al. (2021), Apigenin Induces Autophagy and Cell Death by Targeting EZH2 under Hypoxia Conditions in Gastric Cancer Cells International Journal of Molecular Sciences, 22(24).
  PMID:  34948250
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  S Maharjan et al. (2021), Apoptosis Enhances the Replication of Human Coronavirus OC43 Viruses, 13(11).
  PMID:  34835005
• Species: Bovine
  Sample Types: Whole Cells
  Applications: Bioassay

  P Li et al. (2021), LIF, a mitogen for choroidal endothelial cells, protects the choriocapillaris: implications for prevention of geographic atrophy Embo Molecular Medicine, 0(0):e14511.
  PMID:  34779136
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  HS Gil et al. (2021), AKF-D52, a Synthetic Phenoxypyrimidine-Urea Derivative, Triggers Extrinsic/Intrinsic Apoptosis and Cytoprotective Autophagy in Human Non-Small Cell Lung Cancer Cells Oncogene, 13(22).
  PMID:  34831003
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  JY Yoon et al. (2021), Lucanthone, Autophagy Inhibitor, Enhances the Apoptotic Effects of TRAIL through miR-216a-5p-Mediated DR5 Upregulation and DUB3-Mediated Mcl-1 Downregulation International Journal of Molecular Sciences, 23(1).
  PMID:  35008442
• Species: Mouse
  Sample Types: Whole Cells
  Applications: Flow Cytometry

  M Kosic et al. (2021), 3-Methyladenine prevents energy stress-induced necrotic death of melanoma cells through autophagy-independent mechanisms Journal of pharmacological sciences, 147(1):156-167.
  PMID:  34294367
• Species: Human
  Sample Types: Whole Cells
  Applications: Cell Culture

  Y Yao et al. (2021), Selenium-GPX4 axis protects follicular helper T cells from ferroptosis Nature Immunology, 22(9):1127-1139.
  PMID:  34413521
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  N Ustyanovsk et al. (2021), Galectin-9 Triggers Neutrophil-Mediated Anticancer Immunity Biomedicines, 10(1).
  PMID:  35052746
• Species: Mouse
  
  Applications: Bioassay

  H Ahn et al. (2021), Parabens disrupt non-canonical inflammasome activation International immunopharmacology, 101(0):108196.
  PMID:  34601332
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  E Muscolino et al. (2021), Species-Specific Inhibition of Necroptosis by HCMV UL36 Viruses, 13(11).
  PMID:  34834942
• Species: Human
  Sample Types: Whole Cells
  Applications: Cell Culture

  J Mann et al. (2020), BAD sensitizes breast cancer cells to docetaxel with increased mitotic arrest and necroptosis Sci Rep, 10(1):355.
  PMID:  31942016
• Species: Mouse
  Sample Types: Whole Cells
  Applications: Cell Culture

  A Kratochvíl et al. (2020), Osteogenic impact of pro-apoptotic caspase inhibitors in MC3T3-E1 cells Sci Rep, 10(1):7489.
  PMID:  32366890
• Species: Human
  Sample Types: cell culture
  

  R Liu et al. (2020), Monoglyceride lipase mediates tumor-suppressive effects by promoting degradation of X-linked inhibitor of apoptosis protein Cell Death Differ., 0(0).
  PMID:  32376875
• Species: Human
  Sample Types: Whole Cells
  Applications: Cell Culture

  JE Jang et al. (2020), PERK/NRF2 and autophagy form a resistance mechanism against G9a inhibition in leukemia stem cells J. Exp. Clin. Cancer Res., 39(1):66.
  PMID:  32293500
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  HK Park et al. (2020), Combination of Arsenic Trioxide and Valproic Acid Efficiently Inhibits Growth of Lung Cancer Cells via G2/M-Phase Arrest and Apoptotic Cell Death Int J Mol Sci, 21(7).
  PMID:  32290325
• Species: Mouse
  Sample Types: Whole Cells
  Applications: Bioassay

  C Liao et al. (2020), Activation of JNK signaling promotes all-trans retinal-induced photoreceptor apoptosis in mice J. Biol. Chem., 0(0).
  PMID:  32265302
• Species: Human
  Sample Types: cell culture
  

  J Wang et al. (2020), Skp2 depletion reduces tumor-initiating properties and promotes apoptosis in synovial sarcoma Transl Oncol, 13(10):100809.
  PMID:  32623326
• Species: Mouse
  Sample Types: Whole Cells
  Applications: Cell Culture

  JH Kang et al. (2020), Dual role of phosphatidylserine and its receptors in osteoclastogenesis Cell Death Dis, 11(7):497.
  PMID:  32612123
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  H Lee et al. (2020), Energy-stress-mediated AMPK activation inhibits ferroptosis Nat. Cell Biol., 22(2):225-234.
  PMID:  32029897
• Species: Human
  Sample Types: Whole Cells
  Applications: Cell Culture

  Y Xu et al. (2020), Novel Small Molecular Compound AE-848 Potently Induces Human Multiple Myeloma Cell Apoptosis by Modulating the NF-&kappaB and PI3K/Akt/mTOR Signaling Pathways OncoTargets and Therapy, 13(0):13063-13075.
  PMID:  33376355
• Species: Human
  Sample Types: Whole Cells
  Applications: Cell Culture

  A Murai et al. (2020), Synergistic apoptotic effects in cancer cells by the combination of CLK and Bcl-2 family inhibitors PLoS ONE, 15(10):e0240718.
  PMID:  33064779
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  CA Iannuzzi et al. (2020), Pharmacological Inhibition of WEE1 Potentiates the Antitumoral Effect of the dl922-947 Oncolytic Virus in Malignant Mesothelioma Cell Lines Int J Mol Sci, 21(19).
  PMID:  33020398
• Species: Human
  Sample Types: Whole Cells
  Applications: Cell Culture

  KM Lee et al. (2020), Combined the SMAC mimetic and BCL2 inhibitor sensitizes neoadjuvant chemotherapy by targeting necrosome complexes in tyrosine aminoacyl-tRNA synthase-positive breast cancer Breast Cancer Res, 22(1):130.
  PMID:  33239070
• Species: Mouse
  Sample Types: Whole Cells
  Applications: Inhibition

  J Sun et al. (2020), The Pseudomonas aeruginosa protease LasB directly activates IL-1&beta EBioMedicine, 60(0):102984.
  PMID:  32979835
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  SY Park et al. (2020), Reduction in MLKL-mediated endosomal trafficking enhances the TRAIL-DR4/5 signal to increase cancer cell death Cell Death Dis, 11(9):744.
  PMID:  32917855
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  KJ Min et al. (2020), Induction of Lysosomal Membrane Permeabilization Is a Major Event of FTY720-Mediated Non-Apoptotic Cell Death in Human Glioma Cells Cancers (Basel), 12(11).
  PMID:  33207629
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  Q Zhong et al. (2020), Clustering of Tir during enteropathogenic E. coli infection triggers calcium influx-dependent pyroptosis in intestinal epithelial cells PloS Biology, 18(12):e3000986.
  PMID:  33378358
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  PC Hsu et al. (2020), Chrysophanol Regulates Cell Death, Metastasis, and Reactive Oxygen Species Production in Oral Cancer Cell Lines Evid Based Complement Alternat Med, 2020(0):5867064.
  PMID:  32595733
• Species: Mouse
  Sample Types: Organotypic Tissue Slice
  Applications: Bioassay

  G Park et al. (2020), Caspase Activation and Caspase-Mediated Cleavage of APP Is Associated with Amyloid beta-Protein-Induced Synapse Loss in Alzheimer's Disease Cell Rep, 31(13):107839.
  PMID:  32610140
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  JH Kim et al. (2020), Involvement of the NF-&kappaB signaling pathway in proliferation and invasion inhibited by Zwint-1 deficiency in Pancreatic Cancer Cells Journal of Cancer, 11(19):5601-5611.
  PMID:  32913455
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  F Ito et al. (2020), Asbestos conceives Fe(II)-dependent mutagenic stromal milieu through ceaseless macrophage ferroptosis and beta-catenin induction in mesothelium Redox Biol, 36(0):101616.
  PMID:  32863225
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  SA Shahriyar et al. (2020), Upregulation of DR5 and Downregulation of Survivin by IITZ-01, Lysosomotropic Autophagy Inhibitor, Potentiates TRAIL-Mediated Apoptosis in Renal Cancer Cells via Ubiquitin-Proteasome Pathway Cancers (Basel), 12(9).
  PMID:  32825566
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  IH Yang et al. (2020), Cryptotanshinone chemosensitivity potentiation by TW-37 in human oral cancer cell lines by targeting STAT3-Mcl-1 signaling Cancer Cell Int., 20(0):405.
  PMID:  32863764
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  VK Kashyap et al. (2019), Therapeutic efficacy of a novel ?III/?IV-tubulin inhibitor (VERU-111) in pancreatic cancer J. Exp. Clin. Cancer Res., 38(1):29.
  PMID:  30674344
• Species: Human
  Sample Types: Primary Cells
  Applications: Bioassay

  D Yamasoba et al. (2019), N4BP1 restricts HIV-1 and its inactivation by MALT1 promotes viral reactivation Nat Microbiol, 0(0).
  PMID:  31133753
• Species: Mouse
  
  

  K Tsuchiya et al. (2019), Caspase-1 initiates apoptosis in the absence of gasdermin D Nat Commun, 10(1):2091.
  PMID:  31064994
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  SM Woo et al. (2019), Axl Inhibitor R428 Enhances TRAIL-Mediated Apoptosis Through Downregulation of c-FLIP and Survivin Expression in Renal Carcinoma Int J Mol Sci, 20(13).
  PMID:  31269715
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  HD Cho et al. (2019), Solid state fermentation process with Aspergillus kawachii enhances the cancer-suppressive potential of silkworm larva in hepatocellular carcinoma cells BMC Complement Altern Med, 19(1):241.
  PMID:  31488109
• Species: Mouse
  Sample Types: Whole Cells
  Applications: Bioassay

  PR Mittelstad et al. (2019), Glucocorticoids Oppose Thymocyte Negative Selection by Inhibiting Helios and Nur77 J. Immunol., 0(0).
  PMID:  31527196
• Species: Human
  Sample Types: Tissue Explant
  Applications: Bioassay

  J Riegger et al. (2019), Evidence of necroptosis in osteoarthritic disease: investigation of blunt mechanical impact as possible trigger in regulated necrosis Cell Death Dis, 10(10):683.
  PMID:  31527653
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  SJ Choi et al. (2019), Pseudolaric Acid B Induces Growth Inhibition and Caspase-Dependent Apoptosis on Head and Neck Cancer Cell lines through Death Receptor 5 Molecules, 24(20).
  PMID:  31623058
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  SP O'Hara et al. (2019), The transcription factor ETS1 promotes apoptosis resistance of senescent cholangiocytes by epigenetically up-regulating the apoptosis suppressor BCL2L1 J. Biol. Chem., 0(0).
  PMID:  31659122
• Species: Mouse
  Sample Types: Whole Cells
  Applications: Bioassay

  R Madhi et al. (2019), Platelet IP6K1 regulates neutrophil extracellular trap-microparticle complex formation in acute pancreatitis JCI Insight, 0(0).
  PMID:  31593553
• Species: Mouse
  Sample Types: Whole Cells
  Applications: Bioassay

  M Dileepan et al. (2019), Regulation of Eosinophil Recruitment and Allergic Airway Inflammation by Tropomyosin Receptor Kinase A J. Immunol., 0(0).
  PMID:  31871023
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  AR Lee et al. (2019), Lercanidipine Synergistically Enhances Bortezomib Cytotoxicity in Cancer Cells via Enhanced Endoplasmic Reticulum Stress and Mitochondrial Ca2+ Overload Int J Mol Sci, 20(24).
  PMID:  31817163
• Species: Human
  Sample Types: Whole Cells
  Applications: FACS

  JH Kim et al. (2019), Non-SMC condensin I complex subunit H mediates mature chromosome condensation and DNA damage in pancreatic cancer cells Sci Rep, 9(1):17889.
  PMID:  31784646
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  S Yan et al. (2019), PFKFB3 Inhibition Attenuates Oxaliplatin-Induced Autophagy and Enhances Its Cytotoxicity in Colon Cancer Cells Int J Mol Sci, 20(21).
  PMID:  31671668
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  DE Kim et al. (2019), Deficiency in the DNA repair protein ERCC1 triggers a link between senescence and apoptosis in human fibroblasts and mouse skin Aging Cell, 0(0):e13072.
  PMID:  31737985
• Species: Human
  Sample Types: Whole Cells
  

  B Hu et al. (2018), Herbal formula YGJDSJ inhibits anchorage-independent growth and induces anoikis in hepatocellular carcinoma Bel-7402 cells BMC Complement Altern Med, 18(1):17.
  PMID:  29338725
• Species: Mouse
  Sample Types: Whole Cells
  Applications: Bioassay

  Y Wang et al. (2018), Neutrophil extracellular trap-microparticle complexes enhance thrombin generation via the intrinsic pathway of coagulation in mice Sci Rep, 8(1):4020.
  PMID:  29507382
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  SH Jung et al. (2018), Integrin ?6?4-Src-AKT signaling induces cellular senescence by counteracting apoptosis in irradiated tumor cells and tissues Cell Death Differ., 0(0).
  PMID:  29786073
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  H Wang et al. (2018), Pseudopodium-enriched atypical kinase 1 mediates angiogenesis by modulating GATA2-dependent VEGFR2 transcription Cell Discov, 4(0):26.
  PMID:  29872538
• Species: Mouse
  Sample Types: Whole Cells
  Applications: Bioassay

  S Bowling et al. (2018), P53 and mTOR signalling determine fitness selection through cell competition during early mouse embryonic development Nat Commun, 9(1):1763.
  PMID:  29720666
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  SU Seo et al. (2018), mTORC1/2 inhibitor and curcumin induce apoptosis through lysosomal membrane permeabilization-mediated autophagy Oncogene, 0(0).
  PMID:  29849119
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  SU Seo et al. (2018), Z-FL-COCHO, a cathepsin S inhibitor, enhances oxaliplatin-mediated apoptosis through the induction of endoplasmic reticulum stress Exp. Mol. Med., 50(8):107.
  PMID:  30120227
• Species: Human
  Sample Types: Whole Cells
  

  JM Yun et al. (2018), Involvement of Up-Regulation of DR5 Expression and Down-Regulation of c-FLIP in Niclosamide-Mediated TRAIL Sensitization in Human Renal Carcinoma Caki Cells Molecules, 23(9).
  PMID:  30189637
• Species: Mouse
  Sample Types: Whole Cells
  Applications: Bioassay

  Y Zhang et al. (2018), BAP1 links metabolic regulation of ferroptosis to tumour suppression Nat. Cell Biol., 0(0).
  PMID:  30202049
• Species: Human
  Sample Types: Whole Cells
  Applications: Enzyme Assay

  Z Zhang et al. (2018), Caspase-11-mediated tubular epithelial pyroptosis underlies contrast-induced acute kidney injury Cell Death Dis, 9(10):983.
  PMID:  30250284
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  Y Yue et al. (2018), SARS-Coronavirus Open Reading Frame-3a drives multimodal necrotic cell death Cell Death Dis, 9(9):904.
  PMID:  30185776
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  TW Kim et al. (2018), Kaempferol induces autophagic cell death via IRE1-JNK-CHOP pathway and inhibition of G9a in gastric cancer cells Cell Death Dis, 9(9):875.
  PMID:  30158521
• Species: Mouse
  Sample Types: Whole Cells
  Applications: Bioassay

  A Fiore et al. (2018), Induction of immunosuppressive functions and NF-?B by FLIP in monocytes Nat Commun, 9(1):5193.
  PMID:  30518925
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  WK Saeed et al. (2018), Mismatched effects of receptor interacting protein kinase-3 on hepatic steatosis and inflammation in non-alcoholic fatty liver disease World J. Gastroenterol., 24(48):5477-5490.
  PMID:  30622377
• Species: Mouse
  Sample Types: Whole Cells
  Applications: Bioassay

  BN Singh et al. (2018), A conserved HH-Gli1-Mycn network regulates heart regeneration from newt to human Nat Commun, 9(1):4237.
  PMID:  30315164
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  JW Shin et al. (2018), BCI induces apoptosis via generation of reactive oxygen species and activation of intrinsic mitochondrial pathway in H1299 lung cancer cells Sci China Life Sci, 0(0).
  PMID:  29524123
• Species: Human
  Sample Types: Whole Cells
  Applications: Cell Culture

  AJ Lakhter et al. (2018), Beta cell extracellular vesicle miR-21-5p cargo is increased in response to inflammatory cytokines and serves as a biomarker of type 1 diabetes Diabetologia, 0(0).
  PMID:  29445851
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  HR Cho et al. (2018), 7-Oxygenated cholesterol molecules differentially affect the expression of zonula occludens-1 in vascular smooth muscle cells and monocyte/macrophage cells Biochem. Biophys. Res. Commun., 0(0).
  PMID:  29428726
• Species: Human
  Sample Types: Whole Cells
  

  XH Wang et al. (2017), Oridonin synergizes with Nutlin-3 in osteosarcoma cells by modulating the levels of multiple Bcl-2 family proteins Tumour Biol., 39(6):1010428317701.
  PMID:  28618955
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  RM Stammer et al. (2017), Synergistic Antitumour Properties of viscumTT in Alveolar Rhabdomyosarcoma J Immunol Res, 2017(0):4874280.
  PMID:  28791312
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  Y Shlyakhtin et al. (2017), Dual role of DR5 in death and survival signaling leads to TRAIL resistance in cancer cells Cell Death Dis, 8(8):e3025.
  PMID:  29048428
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  K Harhouri et al. (2017), MG132-induced progerin clearance is mediated by autophagy activation and splicing regulation EMBO Mol Med, 0(0).
  PMID:  28674081
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  MJ Mitchell et al. (2017), Polymeric mechanical amplifiers of immune cytokine-mediated apoptosis Nat Commun, 8(0):14179.
  PMID:  28317839
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  HJ Kim et al. (2017), Shikonin-induced necroptosis is enhanced by the inhibition of autophagy in non-small cell lung cancer cells J Transl Med, 15(1):123.
  PMID:  28569199
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  C Hu et al. (2017), PP2A inhibition from LB100 therapy enhances daunorubicin cytotoxicity in secondary acute myeloid leukemia via miR-181b-1 upregulation Sci Rep, 7(1):2894.
  PMID:  28588271
• Species: Rat
  Sample Types: Whole Cells
  Applications: Bioassay

  JC Means et al. (2017), Distinct Mechanisms Underlying Resveratrol-Mediated Protection from Types of Cellular Stress in C6 Glioma Cells Int J Mol Sci, 18(7).
  PMID:  28708069
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  K Kobbenes S et al. (2017), Depletion of the human N-terminal acetyltransferase hNaa30 disrupts Golgi integrity and ARFRP1-localization Biosci. Rep., 0(0).
  PMID:  28356483
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  K Vorá?ová et al. (2017), The cyanobacterial metabolite nocuolin a is a natural oxadiazine that triggers apoptosis in human cancer cells PLoS ONE, 12(3):e0172850.
  PMID:  28253280
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  IY Kim et al. (2017), Ophiobolin A kills human glioblastoma cells by inducing endoplasmic reticulum stress via disruption of thiol proteostasis Oncotarget, 8(63):106740-106752.
  PMID:  29290985
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  E Gómez-Mora et al. (2017), Elevated humoral response to cytomegalovirus in HIV-infected individuals with poor CD4+ T-cell immune recovery PLoS ONE, 12(9):e0184433.
  PMID:  28934217
• Species: Human
  Sample Types: Recombinant Protein
  Applications: Bioassay

  H Ahn et al. (2017), Lentinan from shiitake selectively attenuates AIM2 and non-canonical inflammasome activation while inducing pro-inflammatory cytokine production Sci Rep, 7(1):1314.
  PMID:  28465544
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  Bo Ra You et al. (2017), Suberoylanilide hydroxamic acid increases anti-cancer effect of tumor necrosis factor-? through up-regulation of TNF receptor 1 in lung cancer cells. Oncotarget, 0(0):1949-2553.
  PMID:  28099148
• Species: Primate - Chlorocebus pygerythrus (Vervet Monkey)
  Sample Types: Whole Cells
  Applications: Bioassay

  (2016), RhoA Proteolysis Regulates the Actin Cytoskeleton in Response to Oxidative Stress PLoS ONE, 11(12):e0168641.
  PMID:  27992599
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  (2016), A Subpopulation of the K562 Cells Are Killed by Curcumin Treatment after G2/M Arrest and Mitotic Catastrophe PLoS ONE, 11(11):e0165971.
  PMID:  27832139
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  Jing Fang (2016), A calcium- and calpain-dependent pathway determines the response to lenalidomide in myelodysplastic syndromes Nat Med, 0(0).
  PMID:  27294874
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  A Sallmyr et al. (2016), Inhibiting Mitochondrial DNA Ligase III? Activates Caspase 1-Dependent Apoptosis in Cancer Cells Cancer Res., 76(18):5431-41.
  PMID:  27503931
• Species: Human
  Sample Types: Whole Cells
  

  (2016), New derivatives of the antimalarial drug Pyrimethamine in the control of melanoma tumor growth: an in vitro and in vivo study J Exp Clin Cancer Res, 35(1):137.
  PMID:  27599543
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  (2016), Lapatinib induces autophagic cell death and differentiation in acute myeloblastic leukemia Onco Targets Ther, 9(0):4453-64.
  PMID:  27499639
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  (2016), Hepatitis C Virus Infection of Cultured Human Hepatoma Cells Causes Apoptosis and Pyroptosis in Both Infected and Bystander Cells Sci Rep, 6(0):37433.
  PMID:  27974850
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  (2016), Multiple Active Compounds from Viscum album L. Synergistically Converge to Promote Apoptosis in Ewing Sarcoma PLoS ONE, 11(9):e0159749.
  PMID:  27589063
• Species: Mouse
  Sample Types: Whole Cells
  Applications: Bioassay

  (2016), Anti-apoptotic Effects of Human Wharton's Jelly-derived Mesenchymal Stem Cells on Skeletal Muscle Cells Mediated via Secretion of XCL1 Mol Ther, 0(0).
  PMID:  27434589
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  (2016), Targeted inhibition of Polo-like kinase 1 by a novel small-molecule inhibitor induces mitotic catastrophe and apoptosis in human bladder cancer cells J. Cell. Mol. Med, 0(0).
  PMID:  27878946
• Species: Mouse
  Sample Types: In Vivo
  Applications: In Vivo

  (2016), Knockdown of RIPK1 Markedly Exacerbates Murine Immune-Mediated Liver Injury through Massive Apoptosis of Hepatocytes, Independent of Necroptosis and Inhibition of NF-?B J Immunol, 0(0).
  PMID:  27605011
• Species: Mouse
  Sample Types: Whole Cells
  

  O Arizmendi et al. (2016), Macrophage Apoptosis Triggered by IpaD from Shigella flexneri Infect Immun, 0(0).
  PMID:  27068089
• Species: Mouse
  Sample Types: Whole Cells
  Applications: Bioassay

  Marie-Claude Gaudreau (2016), Heterogeneous Nuclear Ribonucleoprotein L is required for the survival and functional integrity of murine hematopoietic stem cells Sci Rep, 6(0):27379.
  PMID:  27271479
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  (2016), Induction of apoptosis by Armillaria mellea constituent armillarikin in human hepatocellular carcinoma Onco Targets Ther, 9(0):4773-83.
  PMID:  27536140
• Species: Mouse
  Sample Types: Whole Cells
  Applications: Bioassay

  CN LaRock et al. (2016), IL-1? is an innate immune sensor of microbial proteolysis Sci Immunol, 1(2).
  PMID:  28331908
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  Jong-Wook Park (2016), The multi-target drug BAI induces apoptosis in various human cancer cells through modulation of Bcl-xL protein Int. J. Oncol., 49(6):2620-2628.
  PMID:  27840907
• Species: Human
  Sample Types: Whole Cells
  

  Lei et al. (2015), Inhibition of ANKRD1 sensitizes human ovarian cancer cells to endoplasmic reticulum stress-induced apoptosis. Oncogene, 34(4):485-95.
  PMID:  24531715
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  Martelli M et al. (2015), Arsenic trioxide and all-trans retinoic acid target NPM1 mutant oncoprotein levels and induce apoptosis in NPM1-mutated AML cells. Blood, 125(22):3455-65.
  PMID:  25795919
• Species: Rat
  Sample Types: Whole Cells
  

  Sanz R et al. (2015), IgLON cell adhesion molecules are shed from the cell surface of cortical neurons to promote neuronal growth. J Biol Chem, 290(7):4330-42.
  PMID:  25538237
• Species: Human
  Sample Types: Whole Cells
  

  Hernandez-Corbacho M et al. (2015), Tumor Necrosis Factor-alpha (TNFalpha)-induced Ceramide Generation via Ceramide Synthases Regulates Loss of Focal Adhesion Kinase (FAK) and Programmed Cell Death. J Biol Chem, 290(42):25356-73.
  PMID:  26318452
• Species: Human
  Sample Types: Whole Cells
  

  Virard F et al. (2015), Cold Atmospheric Plasma Induces a Predominantly Necrotic Cell Death via the Microenvironment. PLoS ONE, 10(8):e0133120.
  PMID:  26275141
• Species: Human
  Sample Types: Whole Cells
  

  Kaushik et al. (2015), Non-thermal plasma with 2-deoxy-D-glucose synergistically induces cell death by targeting glycolysis in blood cancer cells. Sci Rep, 5(0):8726.
  PMID:  25735798
• Species: Human
  Sample Types: Whole Cells
  

  Tanaka R et al. (2015), Metformin Causes G1-Phase Arrest via Down-Regulation of MiR-221 and Enhances TRAIL Sensitivity through DR5 Up-Regulation in Pancreatic Cancer Cells. PLoS ONE, 10(5):e0125779.
  PMID:  25955843
• Species: Human
  Sample Types: Whole Cells
  

  Callaway J et al. (2015), Source and Purity of Dengue-Viral Preparations Impact Requirement for Enhancing Antibody to Induce Elevated IL-1beta Secretion: A Primary Human Monocyte Model. PLoS ONE, 10(8):e0136708.
  PMID:  26301593
• Species: Rat
  Sample Types: Whole Cells
  

  Chung K et al. (2015), Calpain Determines the Propensity of Adult Hippocampal Neural Stem Cells to Autophagic Cell Death Following Insulin Withdrawal. Stem Cells, 33(10):3052-64.
  PMID:  26086870
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  Sanyal A et al. (2015), A novel link between Fic (filamentation induced by cAMP)-mediated adenylylation/AMPylation and the unfolded protein response. J Biol Chem, 290(13):8482-99.
  PMID:  25601083
• Species: Human
  Sample Types: Whole Cells
  

  Tanaka N et al. (2015), Wee-1 Kinase Inhibition Sensitizes High-Risk HPV+ HNSCC to Apoptosis Accompanied by Downregulation of MCl-1 and XIAP Antiapoptotic Proteins. Clin Cancer Res, 21(21):4831-44.
  PMID:  26124202
• Species: Mouse
  Sample Types: Whole Tissue
  

  Yang Z et al. (2015), Mesenchymal Wnt/beta-Catenin Signaling Controls Epithelial Stem Cell Homeostasis in Teeth by Inhibiting the Antiapoptotic Effect of Fgf10. Stem Cells, 33(5):1670-81.
  PMID:  25693510
• Species: Human
  Sample Types: Whole Cells
  

  Braun F et al. (2015), Inhibition of methyltransferases accelerates degradation of cFLIP and sensitizes B-cell lymphoma cells to TRAIL-induced apoptosis. PLoS ONE, 10(3):e0117994.
  PMID:  25738497
• Species: Human
  Sample Types: Whole Cells
  

  French R et al. (2015), Cytoplasmic levels of cFLIP determine a broad susceptibility of breast cancer stem/progenitor-like cells to TRAIL. Mol Cancer, 14(0):209.
  PMID:  26667821
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  Mhaidat N et al. (2014), 5-Fluorouracil-induced apoptosis in colorectal cancer cells is caspase-9-dependent and mediated by activation of protein kinase C-delta Oncol Lett, 8(2):699-704.
  PMID:  25013487
• 
  
  

  Wang et al. (2014), Purified vitexin compound 1 induces apoptosis through activation of FOXO3a in hepatocellular carcinoma. Oncol Rep, 31(1):488-96.
  PMID:  24247909
• Species: Human
  Sample Types: Whole Cells
  

  Panzarini et al. (2014), Rose Bengal acetate photodynamic therapy (RBAc-PDT) induces exposure and release of Damage-Associated Molecular Patterns (DAMPs) in human HeLa cells. PLoS ONE, 9(8):e105778.
  PMID:  25140900
• Species: Human
  Sample Types: Cell Lysates
  Applications: Bioassay

  Jang et al. (2014), TRAIL enhances apoptosis of human hepatocellular carcinoma cells sensitized by hepatitis C virus infection: therapeutic implications. PLoS ONE, 9(6):e98171.
  PMID:  24927176
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  Horinaka et al. (2014), Myeloid zinc finger 1 mediates sulindac sulfide-induced upregulation of death receptor 5 of human colon cancer cells. Sci Rep, 4(0):6000.
  PMID:  25102912
• Species: Mouse
  Sample Types: Whole Cells
  Applications: Bioassay

  Bulau A et al. (2014), Role of caspase-1 in nuclear translocation of IL-37, release of the cytokine, and IL-37 inhibition of innate immune responses. Proc Natl Acad Sci U S A, 111(7):2650-5.
  PMID:  24481253
• Species: Human
  Sample Types: Whole Cells
  

  You B et al. (2014), PX-12 inhibits the growth of A549 lung cancer cells via G2/M phase arrest and ROS-dependent apoptosis. Int J Oncol, 44(1):301-8.
  PMID:  24172913
• Species: Mouse
  Sample Types: Whole Cells
  

  Liu B et al. (2014), Apoptosis and pro-inflammatory cytokine response of mast cells induced by influenza A viruses. PLoS ONE, 9(6):e100109.
  PMID:  24923273
• Species: Human
  Sample Types: Whole Cells
  

  You B et al. (2014), Suberoylanilide hydroxamic acid-induced HeLa cell death is closely correlated with oxidative stress and thioredoxin 1 levels. Int J Oncol, 44(5):1745-55.
  PMID:  24626405
• Species: Mouse
  Sample Types: Whole Cells
  

  Imbeault E et al. (2014), Nlrx1 regulates neuronal cell death. Mol Brain, 7(0):90.
  PMID:  25540124
• Species: Human
  Sample Types: Whole Cells
  

  Teigler J et al. (2014), Late endosomal trafficking of alternative serotype adenovirus vaccine vectors augments antiviral innate immunity. J Virol, 88(18):10354-63.
  PMID:  24991003
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  Yan S et al. (2014), The PPARgamma agonist Troglitazone induces autophagy, apoptosis and necroptosis in bladder cancer cells. Cancer Gene Ther, 21(5):188-93.
  PMID:  24853624
• Species: Mouse
  Sample Types: In Vivo
  

  Mueller-Ortiz S et al. (2014), The receptor for the complement C3a anaphylatoxin (C3aR) provides host protection against Listeria monocytogenes-induced apoptosis. J Immunol, 193(3):1278-89.
  PMID:  24981453
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  Park W (2014), Anti-apoptotic effect of caspase inhibitors on H(2)O(2)-treated HeLa cells through early suppression of its oxidative stress. Oncol Rep, 31(5):2413-21.
  PMID:  24627148
• Species: Mouse
  Sample Types: In Vivo
  Applications: In Vivo

  Wang et al. (2014), Interleukin 17A promotes pneumococcal clearance by recruiting neutrophils and inducing apoptosis through a p38 mitogen-activated protein kinase-dependent mechanism in acute otitis media. Infect Immun, 82(6):2368-77.
  PMID:  24664502
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  Choi et al. (2014), Modulation of specificity protein 1 by mithramycin A as a novel therapeutic strategy for cervical cancer. Sci Rep, 4(0):7162.
  PMID:  25418289
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  Singer B et al. (2014), Soluble CEACAM8 interacts with CEACAM1 inhibiting TLR2-triggered immune responses. PLoS ONE, 9(4):e94106.
  PMID:  24743304
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  Shi Y et al. (2014), ROS-dependent activation of JNK converts p53 into an efficient inhibitor of oncogenes leading to robust apoptosis. Cell Death Differ, 21(4):612-23.
  PMID:  24413150
• Species: Mouse
  Sample Types: Whole Cells
  Applications: Bioassay

  Mukherjee P et al. (2013), Activation of the innate signaling molecule MAVS by bunyavirus infection upregulates the adaptor protein SARM1, leading to neuronal death. Immunity, 38(4):705-16.
  PMID:  23499490
• Species: Human
  Sample Types: Whole Cells
  

  Li C et al. (2013), Novel proteolytic microvesicles released from human macrophages after exposure to tobacco smoke. Am J Pathol, 182(5):1552-62.
  PMID:  23499464
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  Han B et al. (2013), Valproic acid inhibits the growth of HeLa cervical cancer cells via caspase-dependent apoptosis. Oncol Rep, 30(6):2999-3005.
  PMID:  24064712
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  Koto K et al. (2013), Zoledronic acid significantly enhances radiationinduced apoptosis against human fibrosarcoma cells by inhibiting radioadaptive signaling. Int J Oncol, 42(2):525-34.
  PMID:  23242142
• Species: Mouse
  Sample Types: Whole Tissue
  

  Anders et al. (2013), Ex vivo modeling of chemical synergy in prenatal kidney cystogenesis. PLoS ONE, 8(3):e57797.
  PMID:  23554868
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  Schindler A et al. (2013), Hexokinase 1 blocks apoptotic signals at the mitochondria. Cell Signal, 25(12):2685-92.
  PMID:  24018046
• Species: Rat
  Sample Types: Whole Cells
  Applications: Bioassay

  Zhang et al. (2013), Cerebral ischemia-reperfusion-induced autophagy protects against neuronal injury by mitochondrial clearance. Autophagy, 9(9):1321-33.
  PMID:  23800795
• Species: Drosophila
  Sample Types: Whole Cells
  

  Jin et al. (2013), Brahma is essential for Drosophila intestinal stem cell proliferation and regulated by Hippo signaling. Elife, 2(0):e00999.
  PMID:  24137538
• Species: Human
  Sample Types: Whole Cells
  Applications: Cell Culture

  McCloy R et al. (2013), Role of endoplasmic reticulum stress induction by the plant toxin, persin, in overcoming resistance to the apoptotic effects of tamoxifen in human breast cancer cells. Br J Cancer, 109(12):3034-41.
  PMID:  24178758
• Species: Mouse
  Sample Types: Whole Cells
  

  Magnifico S et al. (2013), NAD+ acts on mitochondrial SirT3 to prevent axonal caspase activation and axonal degeneration. FASEB J, 27(12):4712-22.
  PMID:  23975935
• Species: Human
  Sample Types: Whole Cells
  

  Xi et al. (2013), The interplays between autophagy and apoptosis induced by enterovirus 71. PLoS ONE, 8(2):e56966.
  PMID:  23437282
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  Shin H et al. (2013), PX-12-induced HeLa cell death is associated with oxidative stress and GSH depletion. Oncol Lett, 6(6):1804-1810.
  PMID:  24260080
• Species: Mouse
  Sample Types: Whole Cells
  

  Lamothe B et al. (2013), TAK1 is essential for osteoclast differentiation and is an important modulator of cell death by apoptosis and necroptosis. Mol Cell Biol, 33(3):582-95.
  PMID:  23166301
• Species: Human
  Sample Types: Whole Cells
  

  Yang H et al. (2013), Bombesin analogue-mediated delivery preferentially enhances the cytotoxicity of a mitochondria-disrupting peptide in tumor cells. PLoS ONE, 8(2):e57358.
  PMID:  23451211
• Species: Human
  Sample Types: Whole Cells
  

  Maqbool M et al. (2013), Regulation of hepatitis C virus replication by nuclear translocation of nonstructural 5A protein and transcriptional activation of host genes. J Virol, 87(10):5523-39.
  PMID:  23468497
• Species: Human
  Sample Types: Whole Cells
  

  D'Agnillo et al. (2013), Anthrax lethal toxin downregulates claudin-5 expression in human endothelial tight junctions. PLoS ONE, 8(4):e62576.
  PMID:  23626836
• Species: Human
  Sample Types: Cell Lysates
  

  Bielaszewska M et al. (2013), Enterohemorrhagic Escherichia coli hemolysin employs outer membrane vesicles to target mitochondria and cause endothelial and epithelial apoptosis. PLoS Pathog, 9(12):e1003797.
  PMID:  24348251
• Species: Human
  Sample Types: Whole Cells
  

  Chakravarthi B et al. (2013), Inhibition of cancer cell proliferation and apoptosis-inducing activity of fungal taxol and its precursor baccatin III purified from endophytic Fusarium solani. Cancer Cell Int, 13(1):105.
  PMID:  24152585
• Species: Human
  Sample Types: Whole Cells
  

  (2012), dsRNA induces apoptosis through an atypical death complex associating TLR3 to caspase-8. Cell Death Differ., 19(9):1482-94.
  PMID:  22421964
• Species: Human
  Sample Types: Whole Cells
  

  Ikner A et al. (2011), TWEAK Induces Apoptosis through a Death-signaling Complex Comprising Receptor-interacting Protein 1 (RIP1), Fas-associated Death Domain (FADD), and Caspase-8. J. Biol. Chem., 286(24):21546-54.
  PMID:  21525013
• Species: Human
  Sample Types: Whole Cells
  

  Liang X et al. (2010), Toll-like receptor 9 signaling by CpG-B oligodeoxynucleotides induces an apoptotic pathway in human chronic lymphocytic leukemia B cells. Blood, 115(24):5041-52.
  PMID:  20339095
• Species: Human
  Sample Types: Whole Cells
  Applications: Flow Cytometry

  Vucicevic L et al. (2009), AMP-activated protein kinase-dependent and -independent mechanisms underlying in vitro antiglioma action of compound C. Biochem. Pharmacol., 77(11):1684-93.
  PMID:  19428322
• Species: Human
  Sample Types: Whole Cells
  

  Park SJ et al. (2009), Sensitization of imatinib-resistant CML cells to TRAIL-induced apoptosis is mediated through down-regulation of Bcr-Abl as well as c-FLIP. Biochem. J., 420(1):73-81.
  PMID:  19203346
• Species: Mouse
  Sample Types: In Vivo
  

  Sorg H et al. (2009), Effects of erythropoietin in skin wound healing are dose related. FASEB J., 23(9):3049-58.
  PMID:  19403513
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  Park SJ et al. (2009), Trichostatin A sensitizes human ovarian cancer cells to TRAIL-induced apoptosis by down-regulation of c-FLIPL via inhibition of EGFR pathway. Biochem. Pharmacol., 77(8):1328-36.
  PMID:  19426671
• Species: Mouse
  Sample Types: Whole Cells
  

  Son KN et al. (2008), Theiler's virus-induced intrinsic apoptosis in M1-D macrophages is Bax mediated and restricts virus infectivity: a mechanism for persistence of a cytolytic virus. J. Virol., 82(9):4502-10.
  PMID:  18287228
• Species: Avian
  Sample Types: In Vivo
  

  Thompson CK et al. (2008), Caspase inhibitor infusion protects an avian song control circuit from seasonal-like neurodegeneration. J. Neurosci., 28(28):7130-6.
  PMID:  18614682
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  Kim et al. (2008), Active caspase-1-mediated secretion of retinoic acid inducible gene-I. J Immunol, 181(10):7324-31.
  PMID:  18981155
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  Ladewig J et al. (2008), Lineage selection of functional and cryopreservable human embryonic stem cell-derived neurons. Stem Cells, 26(7):1705-12.
  PMID:  18420830
• Species: Mouse
  Sample Types: Whole Cells
  

  Plachta N et al. (2007), Identification of a lectin causing the degeneration of neuronal processes using engineered embryonic stem cells. Nat. Neurosci., 10(6):712-9.
  PMID:  17486104
• Species: Human
  Sample Types: Whole Cells
  Applications: Bioassay

  Petit I et al. (2007), The microtubule-targeting agent CA4P regresses leukemic xenografts by disrupting interaction with vascular cells and mitochondrial-dependent cell death. Blood, 111(4):1951-61.
  PMID:  18024794
• Species: Mouse
  Sample Types: Whole Cells
  Applications: Bioassay

  Park EJ et al. (2007), Bakuchiol-induced caspase-3-dependent apoptosis occurs through c-Jun NH2-terminal kinase-mediated mitochondrial translocation of Bax in rat liver myofibroblasts. Eur. J. Pharmacol., 559(2):115-23.
  PMID:  17292878
• Species: Human
  Sample Types: Whole Cells
  

  Mongiat M et al. (2007), Regulation of the extrinsic apoptotic pathway by the extracellular matrix glycoprotein EMILIN2. Mol. Cell. Biol., 27(20):7176-87.
  PMID:  17698584
• Species: Human
  Sample Types: Cell Lysates
  

  Lee SC et al. (2006), Functional proteomics of resveratrol-induced colon cancer cell apoptosis: caspase-6-mediated cleavage of lamin A is a major signaling loop. Proteomics, 6(8):2386-94.
  PMID:  16518869
• Species: Mouse
  Sample Types: Whole Cells
  Applications: Bioassay

  Murata T et al. (2006), Protective effects of neurotrophic factors on tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis of murine adrenal chromaffin cell line tsAM5D. J. Biol. Chem., 281(32):22503-16.
  PMID:  16772303
• Species: Mouse
  Sample Types: Whole Cells
  

  Yamashita H et al. (2006), Embryonic stem cell-derived neuron models of Parkinson's disease exhibit delayed neuronal death. J. Neurochem., 98(1):45-56.
  PMID:  16805795
• Species: Human
  Sample Types: Whole Cells
  

  Salaun B et al. (2006), TLR3 can directly trigger apoptosis in human cancer cells. J. Immunol., 176(8):4894-901.
  PMID:  16585585
• Species: Human
  Sample Types: Whole Cells
  

  Tsai WS et al. (2006), Enhancement of Apo2L/TRAIL-mediated cytotoxicity in esophageal cancer cells by cisplatin. Mol. Cancer Ther., 5(12):2977-90.
  PMID:  17172403
• Species: Human
  Sample Types: Whole Cells
  

  Karrar A et al. (2006), Human liver sinusoidal endothelial cells induce apoptosis in activated T cells: a role in tolerance induction. Gut, 56(2):243-52.
  PMID:  16840505
• Species: Human
  Sample Types: Cell Lysates
  

  Cheng YL et al. (2005), Anti-proliferative activity of Bupleurum scrozonerifolium in A549 human lung cancer cells in vitro and in vivo. Cancer Lett., 222(2):183-93.
  PMID:  15863267
• Species: Human
  Sample Types: Whole Cells
  

  Aguzzi MS et al. (2004), RGDS peptide induces caspase 8 and caspase 9 activation in human endothelial cells. Blood, 103(11):4180-7.
  PMID:  14982875
• Species: Human
  Sample Types: Whole Cells
  

  Attali G et al. (2004), Increased sensitivity of early apoptotic cells to complement-mediated lysis. Eur. J. Immunol., 34(11):3236-45.
  PMID:  15368275
• Species: Human
  Sample Types: Whole Cells
  

  Furukawa Y et al. (2002), Apaf-1 is a mediator of E2F-1-induced apoptosis. J. Biol. Chem., 277(42):39760-8.
  PMID:  12149244
• Species: Human
  Sample Types: Whole Cells
  

  Edgeworth JD et al. (2002), Cytotoxicity and interleukin-1beta processing following Shigella flexneri infection of human monocyte-derived dendritic cells. Eur. J. Immunol., 32(5):1464-71.
  PMID:  11981835

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