PAMP-12 (human, porcine)
Tocris Bioscience, part of Bio-Techne | Catalog # 6551
Potent MRGPRX2 agonist
Key Product Details
Description
Potent MRGPRX2 agonist
Product Description
PAMP-12 (human, porcine) is a potent endogenous peptide agonist of Mas related GPR X2 (MRGPRX2, EC50 = 57.2 nM). Corresponds to amino acids 9 to 20 of proadrenomedullin.Product Specifications
Molecular Weight
1618.95
Formula
C77H119N25O14
Storage
Store at -20°C
Purity
≥95% (HPLC)
CAS Number
196305-05-2
PubChem ID
16137959
InChI Key
DNUWKYBPCFUDDK-DYQOJKGJSA-N
SMILES
[H]N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 1mg/ml in water |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Lansu In silico design of novel probes for the atypical opioid receptor MRGPRX2. Nat.Chem.Biol. 2017 PMID: 28288109
- Kamohara Identification of MrgX2 as a human G-protein-coupled receptor for proadrenomedullin N-terminal peptides. Biochem.Biophys.Res.Commun. 2005 PMID: 15823563
Product Specific Notices for PAMP-12 (human, porcine)
For research use only
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