PAG 3'-piperazine-4-methylpiperidine
Tocris Bioscience, part of Bio-Techne | Catalog # 7997
Cereblon ligand with terminal piperidine for onward chemistry
Key Product Details
Description
Cereblon ligand with terminal piperidine for onward chemistry
Product Description
Phenyl amino glutarimide (PAG) 3'-piperazine-4-methylpiperidine is a functionalized cereblon ligand for PROTAC® research and development. Incorporates an E3 ligase ligand with a terminal piperidine for onward chemistry to generate Protein Degraders with rigid linkers. Part of a range of functionalized tool molecules for PROTAC R&D.Please contact us for SD files of our available Degrader Building Blocks.
PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
Usage Guidelines
This product is provided for use in onward chemistry. Suitable solvents can be used.Product Specifications
Molecular Weight
494.89
Formula
C21H31N5O2.3HCl
Storage
Store at -20°C
Purity
≥95% (HPLC)
Chemical Name
3-[[3-[4-(Piperidin-4-ylmethyl)piperazin-1-yl]phenyl]amino]piperidine-2,6-dione trihydrochloride
InChI Key
TUDPXLYEYHIBQE-UHFFFAOYSA-N
SMILES
O=C(N1)C(NC2=CC(N3CCN(CC3)CC4CCNCC4)=CC=C2)CCC1=O.Cl.Cl.Cl
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Product Specific Notices for PAG 3'-piperazine-4-methylpiperidine
For research use only
Loading...
Loading...