PAG 3'-fluoro-4'-piperazine

Name: PAG 3'-fluoro-4'-piperazine
Brand: Tocris Bioscience
SKU: 7994

Tocris Bioscience, part of Bio-Techne | Catalog # 7994

COA / SDS

Functionalized cereblon ligand for PROTAC development

Key Product Details

Description:	Functionalized cereblon ligand for PROTAC development
Chemical Name:	3-[[3-Fluoro-4-(1-piperazinyl)phenyl]amino]-2,6-piperidinedione dihydrochloride
Purity:	≥95% (HPLC)
Molecular Weight:	379.26

View Full Technical Details for PAG 3'-fluoro-4'-piperazine

Technical Data
Citations

Biological Activity for PAG 3'-fluoro-4'-piperazine

Phenyl amino glutarimide (PAG) 3'-fluoro-4'-piperazine is a functionalized cereblon ligand for PROTAC^® research and development; incorporates an E3 ligase ligand with a terminal piperazine for onward chemistry to generate Protein Degraders with rigid linkers. Part of a range of functionalized tool molecules for PROTAC^® Degrader R&D.

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC^® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Technical Data for PAG 3'-fluoro-4'-piperazine

M. Wt	379.26
Formula	C₁₅H₁₉FN₄O₂.2HCl
Storage	Store at -20°C
Purity	≥95% (HPLC)
InChi Key	JQICJDZAUVKCAJ-UHFFFAOYSA-N
Smiles	O=C(N1)C(NC2=CC(F)=C(C=C2)N3CCNCC3)CCC1=O.Cl.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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Product Documents for PAG 3'-fluoro-4'-piperazine

COA

Certificate of Analysis

To download a Certificate of Analysis, please select a batch below.