Orexin B (human)

Tocris Bioscience, part of Bio-Techne | Catalog # 1456

Endogenous agonist at OX1 and OX2
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Key Product Details

Description

Endogenous agonist at OX1 and OX2

View all Orexin Receptor Agonists »

Product Description

Orexin B (human) is an endogenous agonist at orexin receptors (Ki values are 420 and 36 nM for OX1 and OX2 receptors, respectively). Stimulates feeding following central administration and may be involved in the control of sleep-wake cycle and other hypothalamic functions. Also neuroprotective for dopaminergic neurons in rat midbrain cultures.

Product Specifications

Molecular Weight

2899.36

Formula

C123H212N44O35S

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

205640-91-1

PubChem ID

90479794

InChI Key

DHBREICAXZPFDD-WMQZXSDYSA-N

SMILES

[H]N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCSC)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 1mg/ml in water

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Background References

References are publications that support the biological activity of the product.

Product Documents for Orexin B (human)

Certificate of Analysis

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Product Specific Notices for Orexin B (human)

For research use only

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