Olvanil

Name: Olvanil
Brand: tocris
SKU: 0934

Catalog # 0934

Citations (1)

Datasheet / COA / SDS

Order Information

Bio-Techne Corporation

tel: (800) 343-7475 (free phone)

tel: (612) 379-2956

customercare.na@bio-techne.com

Shipping Information

$35 to United States

Products in stock will be shipped in 1-3 business days unless specified.

View Distributors

Key Product Details

Description:	Potent TRPV agonist
Alternative Names:	NE 19550
Chemical Name:	N-Vanillyloleoylamide
Purity:	≥98% (HPLC)
Molecular Weight:	417.63

View Full Technical Details for Olvanil

Biological Activity

Potent vanilloid receptor agonist (pEC₅₀ values are 8.1 and 7.7 at rat and human VR1 receptors respectively). Also blocks anandamide uptake (IC₅₀ = 9 μM) and may bind to CB₁ cannabinoid receptors. Antinociceptive following systemic administration.

Technical Data

M. Wt	417.63
Formula	C₂₆H₄₃NO₃
Storage	Desiccate at -20°C
Purity	≥98% (HPLC)
CAS Number	58493-49-5
PubChem ID	5311093
InChi Key	OPZKBPQVWDSATI-KHPPLWFESA-N
Smiles	CCCCCCCC\C=C/CCCCCCCC(=O)NCC1=CC=C(O)C(OC)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mM
Solubility
	DMSO	100
	ethanol	25

Preparing Stock Solutions

The following data is based on the product molecular weight 417.63.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.39 mL	11.97 mL	23.94 mL
5 mM	0.48 mL	2.39 mL	4.79 mL
10 mM	0.24 mL	1.20 mL	2.39 mL
50 mM	0.05 mL	0.24 mL	0.48 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References

References are publications that support the biological activity of the product.

Di Marzo Interactions between synthetic vanilloids and the endogenous cannabinoid system. FEBS Lett. 1998 PMID: 9801167
Dray NE-19550 and NE-21610, antinociceptive capsaicin analogues: studies on nociceptive fibres of the neonatal rat tail in vitro. Eur.J.Pharmacol. 1990 PMID: 2384136
Janusz Vanilloids. 1. Analogs of capsaicin with antinociceptive and antiinflammatory activity. J.Med.Chem. 1993 PMID: 8410971
Ralevic Cannabinoid activation of recombinant and endogenous vanilloid receptors. Eur.J.Pharmacol. 2001 PMID: 11672565

Citations (1)

Showing 1 - 1 of 1 citation Showing All

Search Title:

Citations are publications that use Bio-Techne products. Selected citations for Olvanil include:

Witte et al. (2002) Use of a fluorescent imaging plate reader--based calcium assay to assess pharmacological differences between the human and rat vanilloid receptor. Am J Physiol Endocrinol Metab. 7:466
PMID: 14599363

There are no citations that match your criteria.

Showing 1 - 1 of 1 citation Showing All

Product Datasheets

COA

Certificate of Analysis

To download a Certificate of Analysis, please select a batch below.

Olvanil

Order Information

Shipping Information

Key Product Details

Complete Your Experiment

Biological Activity

Technical Data

Solubility

Preparing Stock Solutions

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References

Citations (1)

Product Datasheets

COA

Certificate of Analysis

SDS

Bio-Techne Brands

Stay Connected