OLDA
Tocris Bioscience, part of Bio-Techne | Catalog # 1641
Potent and selective endogenous TRPV1 agonist
Key Product Details
Description
Potent and selective endogenous TRPV1 agonist
Alternative Names
N-Oleoyldopamine
Product Description
OLDA is a potent endogenous vanilloid TRPV1 (VR1) receptor agonist (EC50 = 36 nM at hVR1) with low affinity for rCB1 receptors (Ki = 1.6 μM). Potently induces VR1-mediated thermal hyperalgesia in rats in vivo.Product Specifications
Molecular Weight
417.63
Formula
C26H43NO3
Storage
Desiccate at -20°C
Purity
≥98% (HPLC)
Chemical Name
(9Z)-N-[2-(3,4-Dihydroxyphenyl)ethyl]-9-octadecenamide
CAS Number
105955-11-1
PubChem ID
5282106
InChI Key
QQBPLXNESPTPNU-KTKRTIGZSA-N
SMILES
CCCCCCCC\C=C/CCCCCCCC(=O)NCCC1=CC=C(O)C(O)=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 20.88 | 50 | |
| Ethanol | 20.88 | 50 |
Preparing Stock Solutions
for OLDA
The following data is based on the product molecular weight 417.63
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.5 mM | 4.79 mL | 23.94 mL | 47.89 mL |
| 2.5 mM | 0.96 mL | 4.79 mL | 9.58 mL |
| 5 mM | 0.48 mL | 2.39 mL | 4.79 mL |
| 25 mM | 0.10 mL | 0.48 mL | 0.96 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Chu N-OleoylDA, a novel endogenous capsaicin-like lipid that produces hyperalgesia. J.Biol.Chem. 2003 PMID: 12569099
- Butelman Anitallodynic effects of loperamide and fen. against topical capsaicin-induced allodynia in unanesthetized primates. J.Pharmacol.Exp.Ther. 2004 PMID: 15152028
Product Specific Notices for OLDA
For research use only
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