Key Product Details
Description: | Protein phosphatase 1 and 2A inhibitor |
Chemical Name: | 9,10-Deepithio-9,10-didehydroacanthifolicin |
Molecular Weight: | 805.01 |
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Citations for Okadaic acid (28)
Citations are publications that use Bio-Techne products. Selected citations for Okadaic acid include:
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Coates et al.
(2019)
The insect, Galleria mellonella, is a compatible model for evaluating the toxicology of okadaic acid.
Cell Biol Toxicol.
35:219
PMID: 30426330 -
Messal et al.
(2019)
Tissue curvature and apicobasal mechanical tension imbalance instruct cancer morphogenesis.
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566:126
PMID: 30700911 -
Livingstone et al.
(2019)
Secreted Amyloid Precursor Protein-Alpha Promotes Arc Protein Synthesis in Hippocampal Neurons.
Front Mol Neurosci.
12:198
PMID: 31474829 -
Chiu et al.
(2019)
NMDAR-Activated PP1 Dephosphorylates GluN2B to Modulate NMDAR Synaptic Content.
Cell Rep.
28:332
PMID: 31291571 -
Jones et al.
(2018)
Inflammatory but not mitogenic contexts prime synovial fibroblasts for compensatory signaling responses to p38 inhibition.
Sci Signal.
11
PMID: 29511118 -
Pose-Utrilla et al.
(2017)
Excitotoxic inactivation of constitutive oxidative stress detoxification pathway in neurons can be rescued by PKD1.
Nat Commun.
8:2275
PMID: 29273751 -
Kii et al.
(2016)
Selective inhibition of the kinase DYRK1A by targeting its folding process.
Nat Commun.
7:11391
PMID: 27102360 -
Bartley et al.
(2016)
Mammalian FMRP S499 Is Phosphorylated by CK2 and Promotes Secondary Phosphorylation of FMRP.
Eneuro.
3
PMID: 27957526 -
Polito et al.
(2015)
Selective Effects of PDE10A Inhibitors on Striatopallidal Neurons Require Phosphatase Inhibition by DARPP-32(1,2,3).
Biochem Biophys Res Commun.
2
PMID: 26465004 -
Cohen et al.
(2015)
Evolutionary and functional perspectives on signaling from neuronal surface to nucleus.
Neurobiol Dis.
460:88
PMID: 25998737 -
Hullinger et al.
(2015)
Environmental enrichment improves learning and memory and long-term potentiation in young adult rats through a mechanism requiring mGluR5 signaling and sustained activation of p70s6k.
Neurobiol Learn Mem.
125:126
PMID: 26341144 -
Martin et al.
(2014)
IKKα negatively regulates ASC-dependent inflammasome activation.
Nat Commun.
5:4977
PMID: 25266676 -
Chen et al.
(2014)
Prolonged adenosine A1 receptor activation in hypoxia and pial vessel disruption focal cortical ischemia facilitates clathrin-mediated AMPA receptor endocytosis and long-lasting synaptic inhibition in rat hippocampal CA3-CA1 synapses: differential regulat
J Neurosci.
34:9621
PMID: 25031403 -
Thayer et al.
(2013)
Increased neuronal activity fragments the Golgi complex.
Proc Natl Acad Sci U S A.
110:1482
PMID: 23297202 -
Brito et al.
(2013)
Imbalance of p75(NTR)/TrkB protein expression in Huntington's disease: implication for neuroprotective therapies.
Cell Death Dis.
4:e595
PMID: 23598407 -
Bernard et al.
(2013)
Phosphorylation of FMRP and alterations of FMRP complex underlie enhanced mLTD in adult rats triggered by early life seizures.
PLoS One.
59:42736
PMID: 23831253 -
Seto et al.
(2013)
Acute SimV. inhibits K ATP channels of porcine coronary artery myocytes.
J Neurosci.
8:e66404
PMID: 23799098 -
Pradhan and Vijayan
(2013)
Lipid rafts contribute to agonist-induced serine/threonine phosphatase activation and platelet aggregation.
J Neurosci.
11:1612
PMID: 23789860 -
Pribiag and Stellwagen
(2013)
TNF-α Downregulates Inhibitory Neurotransmission through Protein Phosphatase 1-Dependent Trafficking of GABAA Receptors.
Mol Pain.
33:15879
PMID: 24089494 -
Li and Burrell
(2011)
Associative, bidirectional changes in neural signaling utilizing NMDA receptor- and endocannabinoid-dependent mechanisms.
Learn Mem.
18:545
PMID: 21844187 -
Rankovic et al.
(2011)
Modulation of calcium-dependent inactivation of L-type Ca2+ channels via β-adrenergic signaling in thalamocortical relay neurons.
PLoS One.
6:e27474
PMID: 22164209 -
Goffin et al.
(2010)
DA-dependent tuning of striatal inhibitory synaptogenesis.
J Neurosci.
30:2935
PMID: 20181591 -
Bodhinathan et al.
(2010)
Intracellular redox state alters NMDA receptor response during aging through Ca2+/calmodulin-dependent protein kinase II.
J Neurosci.
30:1914
PMID: 20130200 -
Li et al.
(2009)
Activation of glycogen synthase kinase-3 β is required for hyperDA and D2 receptor-mediated inhibition of synaptic NMDA receptor function in the rat prefrontal cortex.
Eneuro.
29:15551
PMID: 20007479 -
Kim et al.
(2008)
Aberrant early-phase ERK inactivation impedes neuronal function in fragile X syndrome.
J Thromb Haemost.
105:4429
PMID: 18332424 -
Stipanovich et al.
(2008)
A phosphatase cascade by which rewarding stimuli control nucleosomal response.
Nature.
453:879
PMID: 18496528 -
Marsden et al.
(2007)
NMDA receptor activation potentiates inhibitory transmission through GABA receptor-associated protein-dependent exocytosis of GABA(A) receptors.
J Neurosci.
27:14326
PMID: 18160640 -
Dart and Leyland
(2001)
Targeting of an A kinase-anchoring protein, AKAP79, to an inwardly rectifying potassium channel, Kir2.1.
J Biol Chem.
276:20499
PMID: 11287423
There are no citations that match your criteria.
Customer Reviews for Okadaic acid (2)
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Species: RatAssay Type: In VitroCell Line/Tissue: Sprague-Dawley rats primary neuronalOkadaic acid for PP2A at 20 nM
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Species: MouseAssay Type: In VitroCell Line/Tissue: CardiomyocytesHL-1 cardiomyocytes were treated with 100 nM fostriecin, 100 nM Okadaic acid or 50 nM 8-bromo-cAMP for 30 min followed by Western blot analysis for pCaMKII expression. Okadaic acid significantly increased phosphorylation of CaMKII; indicating a major role of PP1 in CaMKII dephosphorylation.
There are no reviews that match your criteria.