OB 24 hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 6119

Potent and selective heme oxygenase 1 (HO-1) inhibitor
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Key Product Details

Description

Potent and selective heme oxygenase 1 (HO-1) inhibitor

View all Heme Oxygenase Inhibitors »

Product Description

OB 24 hydrochloride is a potent and selective heme oxygenase 1 (HO-1) inhibitor (IC50 values are 1.9 and >100 μM for HO-1 and HO-2 respectively), reduces protein carbonylation and reactive oxygen species formation in advanced prostate cancer cells (PCA). Inhibits cell proliferation in vitro and PCA tumor growth and lymph node/lung metastases in vivo. Synergizes with Taxol (Cat. No. 1097).

Product Specifications

Molecular Weight

373.67

Formula

C15H17BrN2O2.HCl

Storage

Desiccate at RT

Purity

≥98% (HPLC)

Chemical Name

1-[[2-[2-(4-Bromophenyl)ethyl]-1,3-dioxolan-2-yl]methyl]-1H-imidazole hydrochloride

CAS Number

939825-12-4

PubChem ID

45265865

InChI Key

YSOWYXRHOAXXTG-UHFFFAOYSA-N

SMILES

BrC1=CC=C(C=C1)CCC2(OCCO2)CN3C=CN=C3.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 37.4 100
DMSO 37.37 100

Preparing Stock Solutions for OB 24 hydrochloride

The following data is based on the product molecular weight 373.67

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.68 mL 13.38 mL 26.76 mL
5 mM 0.54 mL 2.68 mL 5.35 mL
10 mM 0.27 mL 1.34 mL 2.68 mL
50 mM 0.05 mL 0.27 mL 0.54 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for OB 24 hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for OB 24 hydrochloride

For research use only

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