NTRC 824
Tocris Bioscience, part of Bio-Techne | Catalog # 5438
Potent and selective non-peptide NTS2 antagonist
Key Product Details
Description
Potent and selective non-peptide NTS2 antagonist
Product Description
NTRC 824 is a potent and selective non-peptide neurotensin (NTS) type-2 receptor antagonist (IC50 = 38 nM). Exhibits >150-fold selectivity for NTS2 over NTS1.Product Specifications
Molecular Weight
553.55
Formula
C25H26F3N3O6S
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
N-[2-[5-[[(4-Methylphenyl)sulfonyl]amino]-3-(2,2,2-trifluoroacetyl)-1H-indol-1-yl]acetyl]-L-leucine
CAS Number
1623002-61-8
PubChem ID
101873359
InChI Key
SOOLLEBJNGCDOZ-FQEVSTJZSA-N
SMILES
O=C(C(F)(F)F)C2=CN(CC(N[C@@H](CC(C)C)C(O)=O)=O)C1=CC=C(NS(C3=CC=C(C)C=C3)(=O)=O)C=C12
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 55.35 | 100 | |
| Ethanol | 55.35 | 100 |
Preparing Stock Solutions
for NTRC 824
The following data is based on the product molecular weight 553.55
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.81 mL | 9.03 mL | 18.07 mL |
| 5 mM | 0.36 mL | 1.81 mL | 3.61 mL |
| 10 mM | 0.18 mL | 0.90 mL | 1.81 mL |
| 50 mM | 0.04 mL | 0.18 mL | 0.36 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
Product Specific Notices for NTRC 824
For research use only
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