NS 3623

Tocris Bioscience, part of Bio-Techne | Catalog # 4462

KV11.1 (hERG) and KV4.3 channel activator; antiarrhythmic
Catalog #
Availability
Size / Price
Qty
4462/50
4462/10
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Description

KV11.1 (hERG) and KV4.3 channel activator; antiarrhythmic

View all Voltage-gated Potassium Channel Activators »

Product Description

NS 3623 is a KV11.1 (hERG) and KV4.3 channel activator. Activates the IKr and Ito currents and displays antiarrhythmic activity. May also act as a partial blocker of KV11.1 channels. Displays selectivity over the key cardiac potassium channels, KV7.1 (KCNQ1) and KV1.5. Suitable for both in vitro and in vivo use.

Product Specifications

Molecular Weight

427.18

Formula

C15H10BrF3N6O

Storage

Store at +4°C

Purity

≥99% (HPLC)

Chemical Name

N-[4-Bromo-2-(1H-tetrazol-5-yl-phenyl]-N'-[3-(trifluoromethyl)phenyl]-urea

CAS Number

343630-41-1

PubChem ID

9954236

InChI Key

JXPULDIATMTIIN-UHFFFAOYSA-N

SMILES

BrC1=CC(C2=NN=NN2)=C(NC(NC3=CC(C(F)(F)F)=CC=C3)=O)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 42.72 100

Preparing Stock Solutions for NS 3623

The following data is based on the product molecular weight 427.18

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.34 mL 11.70 mL 23.41 mL
5 mM 0.47 mL 2.34 mL 4.68 mL
10 mM 0.23 mL 1.17 mL 2.34 mL
50 mM 0.05 mL 0.23 mL 0.47 mL

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

x
=
x

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Product Documents for NS 3623

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for NS 3623

For research use only

Privacy Policy
Cookie Policy
Site Map
© Copyright 2026 Bio-Techne. All Rights Reserved. All trademarks and registered trademarks are the property of Bio-Techne and its brands unless otherwise specified.