NPEC-caged-(1S,3R)-ACPD

Name: NPEC-caged-(1 S ,3 R )-ACPD
Brand: Tocris Bioscience
SKU: 3331

Tocris Bioscience a Bio-Techne Brand

Catalog # 3331

COA / SDS

Discontinued Product

3331 has been discontinued. View all Group I mGluR Agonists products.

Key Product Details

Description:	Caged (1S,3R)-ACPD
Chemical Name:	(1S,3R)-1-(2-Nitrophenyl)ethylcarboxyaminocyclopentane-1,3-dicarboxylic acid
Molecular Weight:	366.32

View Full Technical Details for NPEC-caged-(1S,3R)-ACPD

Biological Activity for NPEC-caged-(1S,3R)-ACPD

NPEC-caged-(1S,3R)-ACPD is an (1S,3R)-ACPD (Cat.No. 0284) caged with the photosensitive 1-(2-nitrophenyl)ethoxycarbonyl (NPEC) group. Extinction coefficient (ε₃₄₇) = 660 M^-1cm^-1, quantum yield (φ) = 0.64. Suitable for near-UV uncaging. No inhibition of GABA-A receptors at concentrations used experimentally.

Technical Data for NPEC-caged-(1S,3R)-ACPD

M. Wt	366.32
Formula	C₁₆H₁₈N₂O₈
Storage	Desiccate at RT
CAS Number	1315379-60-2
PubChem ID	90488832
InChi Key	SKBDCZAPZZBWJU-XOXYBHGNSA-N
Smiles	O=C(N[C@]2([C@](O)=O)C[C@H]([C@](O)=O)CC2)OC(C)C1=C([N+]([O-])=O)C=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for NPEC-caged-(1S,3R)-ACPD

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	water	3.66	10
	DMSO	36.63	100

Preparing Stock Solutions for NPEC-caged-(1S,3R)-ACPD

The following data is based on the product molecular weight 366.32.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.73 mL	13.65 mL	27.30 mL
5 mM	0.55 mL	2.73 mL	5.46 mL
10 mM	0.27 mL	1.36 mL	2.73 mL
50 mM	0.05 mL	0.27 mL	0.55 mL

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References for NPEC-caged-(1S,3R)-ACPD

References are publications that support the biological activity of the product.

Palma-Cerda New caged neurotransmitter analogs selective for glutamate receptor sub-types based on methoxynitroindoline and nitrophenylethoxycarbonyl caging groups. Neuropharmacology. 2012 PMID: 22609535

Citations for NPEC-caged-(1S,3R)-ACPD

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NPEC-caged-(1S,3R)-ACPD

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Biological Activity for NPEC-caged-(1S,3R)-ACPD

Technical Data for NPEC-caged-(1S,3R)-ACPD

Solubility for NPEC-caged-(1S,3R)-ACPD

Preparing Stock Solutions for NPEC-caged-(1S,3R)-ACPD

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for NPEC-caged-(1S,3R)-ACPD

Citations for NPEC-caged-(1S,3R)-ACPD

Product Documents for NPEC-caged-(1S,3R)-ACPD

COA

Certificate of Analysis

SDS

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