[Nle4,D-Phe7]-α-MSH

Tocris Bioscience, part of Bio-Techne | Catalog # 3013

Melanocortin receptor agonist
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Key Product Details

Description

Melanocortin receptor agonist

Alternative Names

Melanotan I,MT-I,NDP-α-MSH

View all Melanocortin Receptor Agonists »

Product Description

[Nle4,D-Phe7]-α-MSH is a synthetic analog of α-MSH that is an agonist at melanocortin receptors (Ki values are 0.085, 0.4, 3.8 and 5.1 nM for MC1, MC3, MC4 and MC5 receptors respectively).

Product Specifications

Molecular Weight

1646.86

Formula

C78H111N21O19

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

75921-69-6

PubChem ID

16132139

InChI Key

UAHFGYDRQSXQEB-PWPYQVNISA-N

SMILES

CCCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 0.6mg/ml in water

Calculators

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Background References

References are publications that support the biological activity of the product.

  • Sawyer 4-Norleucine, 7-D-phenylalanine-α-melanocyte-stimulating hormone: a highly potent α-melanotropin with ultrapotent biological activity. Proc.Natl.Acad.Sci.USA
  • Wikber Melanocortin receptors: perspectives for novel drugs. Eur.J.Pharmacol. 1999 PMID: 10443584

Product Documents

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices

For research use only

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