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Nifedipine

Voltage-gated Calcium Channel Blockers Small Molecule
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1075/100

Key Product Details

Description: CaV1.x blocker
Chemical Name: 1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester
Purity: ≥98% (HPLC)
Molecular Weight: 346.34

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Citations (35)

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Customer Reviews (5)

4.8 out of 5
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  • breast cancer cell viability by a cannabinoid receptor 2 agonist
    Name: Anonymous
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: MCF-7
    We used all these compounds which were dissolved in DMSO and added to fresh culture media. Concentration reference paper PMID: 27186076
    Nifedipine Serum 1075
  • The pharmacological inhibitors for electrophysiology assay
    Name: Anonymous
    Species: Other
    Assay Type: In Vitro
    The following concentrations we were used:1 μM Bay K, 10 μM nifedipine, 10 μM nimodipine, 300 nM omega -agatoxin, 1 μM omega -conotoxin, 5 μM mibefradil, 1 μM tetrodotoxin, 1 μM charybdotoxin, 100 nM iberiotoxin, 10 μM NS11021.
    Nifedipine Serum 1075
  • Blocks L type calcium entry in neurons
    Name: Karthik krishnamurthy
    Species: Rat
    Assay Type: In Vitro
    Cell Line/Tissue: spinal cord neurons
    Effectively blocks KCL mediated L type calcium entry in neurons. Tested in spinal cord neuron cultures at a concentration of 10 micromolar.
    Nifedipine Serum 1075
  • Nifedipine blocks L-type Ca2+ current in primary cardiomyoytes
    Name: Chintan Koyani
    Species: Other
    Assay Type: In Vitro
    Cell Line/Tissue: Primary ventricular cardiomyocytes
    L-type Ca2+ current of guinea pig cardiomyocytes before and after nifedipine (1 µM) superfusion for 5 min. Compared to time-matched rundown, nifedipine significantly blocked L-type Ca2+ current in cardiomyocytes
    Nifedipine Serum 1075
  • Applied to GI smooth muscle in tissue bath
    Name: John Broad
    Species: Human
    Assay Type: In Vitro
    Applied to human GI smooth muscle
    Effective calcium channel blocker

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Certificate of Analysis

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⚠ WARNING: This product can expose you to chemicals including Nifedipine, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov