Nifedipine
Tocris Bioscience, part of Bio-Techne | Catalog # 1075
CaV1.x blocker
Product Description
Nifedipine is a L-type calcium channel blocker.Product Specifications
Molecular Weight
346.34
Formula
C17H18N2O6
Storage
Desiccate at +4°C
Purity
≥98% (HPLC)
Chemical Name
1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester
CAS Number
21829-25-4
PubChem ID
4485
InChI Key
HYIMSNHJOBLJNT-UHFFFAOYSA-N
SMILES
COC(=O)C1=C(C)NC(C)=C(C1C1=CC=CC=C1[N+]([O-])=O)C(=O)OC
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 34.63 | 100 |
Preparing Stock Solutions
for Nifedipine
The following data is based on the product molecular weight 346.34
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.89 mL | 14.44 mL | 28.87 mL |
| 5 mM | 0.58 mL | 2.89 mL | 5.77 mL |
| 10 mM | 0.29 mL | 1.44 mL | 2.89 mL |
| 50 mM | 0.06 mL | 0.29 mL | 0.58 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Stork and Cocks Pharmacological reactivity of human epicardial coronary arteries: phasic and tonic responses to vasoconstrictor agents differentiated by nifed. Br.J.Pharmacol. 1994 PMID: 7889259
Product Specific Notices for Nifedipine
For research use only
⚠ WARNING: This product can expose you to chemicals including Nifedipine, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov
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