Nifedipine

Name: Nifedipine
Brand: Tocris Bioscience
SKU: 1075
Rating: 5 (5 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 1075

(5)

Citations (258)

COA / SDS

CaV1.x blocker

Key Product Details

Description:	Ca_V1.x blocker
Chemical Name:	1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester
Purity:	≥98% (HPLC)
Molecular Weight:	346.34

View Full Technical Details for Nifedipine

Technical Data
Citations / Reviews (5)

Biological Activity for Nifedipine

Nifedipine is a L-type calcium channel blocker.

Technical Data for Nifedipine

M. Wt	346.34
Formula	C₁₇H₁₈N₂O₆
Storage	Desiccate at +4°C
Purity	≥98% (HPLC)
CAS Number	21829-25-4
PubChem ID	4485
InChi Key	HYIMSNHJOBLJNT-UHFFFAOYSA-N
Smiles	COC(=O)C1=C(C)NC(C)=C(C1C1=CC=CC=C1[N+]([O-])=O)C(=O)OC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Nifedipine

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	34.63	100

Preparing Stock Solutions for Nifedipine

The following data is based on the product molecular weight 346.34.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.89 mL	14.44 mL	28.87 mL
5 mM	0.58 mL	2.89 mL	5.77 mL
10 mM	0.29 mL	1.44 mL	2.89 mL
50 mM	0.06 mL	0.29 mL	0.58 mL

Molarity Calculator

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Dilution Calculator

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Reconstitution Calculator

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References for Nifedipine

References are publications that support the biological activity of the product.

Stork and Cocks Pharmacological reactivity of human epicardial coronary arteries: phasic and tonic responses to vasoconstrictor agents differentiated by nifed. Br.J.Pharmacol. 1994 PMID: 7889259

Product Documents for Nifedipine

COA

Certificate of Analysis

To download a Certificate of Analysis, please select a batch below.

SDS

⚠ WARNING: This product can expose you to chemicals including Nifedipine, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov