Neurodazine

Name: Neurodazine
Brand: Tocris Bioscience
SKU: 3656

Tocris Bioscience, part of Bio-Techne | Catalog # 3656

COA / SDS

Induces neurogenesis in mature skeletal muscle cells

Key Product Details

Description:	Induces neurogenesis in mature skeletal muscle cells
Chemical Name:	2-[5-(3-Chlorophenyl)-2-furanyl]-4,5-bis(4-methoxyphenyl)-1H-imidazole
Purity:	≥99% (HPLC)
Molecular Weight:	456.92

View Full Technical Details for Neurodazine

Technical Data
Citations

Biological Activity for Neurodazine

Neurodazine is an induces neurogenesis of non-pluripotent C2C12 myoblasts and cells derived from mature human skeletal muscle. Upregulates the expression of neuron-specific markers in C2C12 cells.

Technical Data for Neurodazine

M. Wt	456.92
Formula	C₂₇H₂₁ClN₂O₃
Storage	Store at +4°C
Purity	≥99% (HPLC)
CAS Number	937807-66-4
PubChem ID	16112820
InChi Key	FEEOFPAEDSMOTO-UHFFFAOYSA-N
Smiles	ClC1=CC=CC(C(O3)=CC=C3C2=NC(C5=CC=C(OC)C=C5)=C(C4=CC=C(OC)C=C4)N2)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Neurodazine

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	DMSO	45.69	100
	ethanol	22.85	50

Preparing Stock Solutions for Neurodazine

The following data is based on the product molecular weight 456.92.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.19 mL	10.94 mL	21.89 mL
5 mM	0.44 mL	2.19 mL	4.38 mL
10 mM	0.22 mL	1.09 mL	2.19 mL
50 mM	0.04 mL	0.22 mL	0.44 mL

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References for Neurodazine

References are publications that support the biological activity of the product.

Halder Combining suppression of stemness with lineage-specific induction leads to conversion of pluripotent cells into functional neurons. Chem.Biol. 2015 PMID: 26590637
Williams Synthetic small molecules that induce neurogenesis in skeletal muscle. J.Am.Chem.Soc. 2007 PMID: 17622149