Nelarabine

Tocris Bioscience, part of Bio-Techne | Catalog # 6359

Purine nuceloside analog; inhibits DNA synthesis
Catalog #
Availability
Size / Price
Qty
6359/10
6359/50
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Description

Purine nuceloside analog; inhibits DNA synthesis

Alternative Names

GW 506U78

View all DNA, RNA and Protein Synthesis Inhibitors »

Product Description

Nelarabine is a nucleoside analog. Metabolized by adenosine deaminase to active metabolite, arabinofuranosylguanine (ara-G). Inhibits DNA synthesis and induces apoptosis. Inhibits growth of human T cell lymphoblastic leukemia cells in vitro and in vivo.

Product Specifications

Molecular Weight

297.27

Formula

C11H15N5O5

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

9-β-D-Arabinofuranosyl-6-methoxy-9H-purin-2-amine

CAS Number

121032-29-9

PubChem ID

3011155

InChI Key

IXOXBSCIXZEQEQ-UHTZMRCNSA-N

SMILES

COC1=C2C(N([C@@H]3O[C@H](CO)[C@@H](O)[C@@H]3O)C=N2)=NC(N)=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 2.97 10 with gentle warming
DMSO 29.73 100

Preparing Stock Solutions for Nelarabine

The following data is based on the product molecular weight 297.27

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.36 mL 16.82 mL 33.64 mL
5 mM 0.67 mL 3.36 mL 6.73 mL
10 mM 0.34 mL 1.68 mL 3.36 mL
50 mM 0.07 mL 0.34 mL 0.67 mL

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

x
=
x

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Background References

References are publications that support the biological activity of the product.

Product Documents for Nelarabine

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Nelarabine

For research use only

Privacy Policy
Cookie Policy
Site Map
© Copyright 2026 Bio-Techne. All Rights Reserved. All trademarks and registered trademarks are the property of Bio-Techne and its brands unless otherwise specified.