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Necrostatin-1

Tocris Bioscience a Bio-Techne Brand

Necrostatin-1 | CAS No. 4311-88-0 | RIP1 kinase inhibitor; inhibits necroptosis
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Key Product Details

Description: RIP1 kinase inhibitor; inhibits necroptosis
Chemical Name: 5-(1H-Indol-3-ylmethyl)-3-methyl-2-thioxo-4-imidazolidinone
Purity: ≥98% (HPLC)
Molecular Weight: 259.33

Citations for Necrostatin-1 (4)

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  • Necroptosis-related studies
    Name: MARINA KOUTSIOUMPA
    Species: Human
    Assay Type: In Vitro
    Combinatorial treatments of Necrostatin-1 with other chemotherapeutic drugs were performed to elucidate the dependance of the latter on the induction of necroptosis. Results were consistent.
  • good necroptosis inhibitor
    Name: Anonymous
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: Caco-2
    100nM of Nec-1 was used to inhibit RIPK1 after administration cells with TNFa, zVADfmk, and smac inhibitors to induce necroptosis, then cell death rate was measured with a commercial kit.
    Necrostatin-1 Serum 2324

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Product Documents for Necrostatin-1

Certificate of Analysis

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