NAN-190 hydrobromide
Tocris Bioscience, part of Bio-Techne | Catalog # 0553
5-HT1A antagonist
Product Description
NAN-190 hydrobromide is a 5-HT1A antagonist.Product Specifications
Molecular Weight
474.40
Formula
C23H27N3O3.HBr
Storage
Store at RT
Purity
≥98% (HPLC)
Chemical Name
1-(2-Methoxyphenyl)-4-(4-phthalimidobutyl)piperazine hydrobromide
CAS Number
115338-32-4
PubChem ID
107966
InChI Key
AXRUEPFPTQYHQD-UHFFFAOYSA-N
SMILES
Br.COC1=C(C=CC=C1)N1CCN(CCCCN2C(=O)C3=CC=CC=C3C2=O)CC1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 4.74 | 10 |
Preparing Stock Solutions
for NAN-190 hydrobromide
The following data is based on the product molecular weight 474.40
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.08 mL | 105.40 mL | 210.79 mL |
| 0.5 mM | 4.22 mL | 21.08 mL | 42.16 mL |
| 1 mM | 2.11 mL | 10.54 mL | 21.08 mL |
| 5 mM | 0.42 mL | 2.11 mL | 4.22 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Glennon Arylpiperazine derivatives as high affinity 5-HT1A serotonin ligands. J.Med.Chem. 1988 PMID: 3172131
- Williams and Glennon NAN-190: an arylpiperazine analog that antagonizes the stimulus effects of the 5-HT1A agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT). Eur.J.Pharmacol. 1988 PMID: 2976673
- Douris Effects of the putative 5-HT1A receptor antagonist NAN-190 on free feeding and on feeding induced by the 5-HT1A receptor agonist 8-OH-DPAT in the rat. Eur.J.Pharmacol. 1992 PMID: 1397037
Product Specific Notices for NAN-190 hydrobromide
For research use only
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