Nafamostat mesylate

Tocris Bioscience, part of Bio-Techne | Catalog # 3081

Serine protease inhibitor; inhibits tryptase
Catalog #
Availability
Size / Price
Qty
3081/10
3081/50
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Description

Serine protease inhibitor; inhibits tryptase

View all TMPRSS2 Inhibitors »

Product Description

Nafamostat mesylate is a broad spectrum serine protease inhibitor. Displays selectivity for human tryptase when used at relatively low concentrations. Reduces eosinophil infiltration, mast cell activation and airway responsiveness in a murine model of asthma. Inhibits SARS-CoV-2 infection in vitro (EC50 = 22.50 μM).

Tocris products are for biomedical research use only. They are not intended for human or veterinary use.

Product Specifications

Molecular Weight

539.59

Formula

C19H17N5O2.2CH4O3S

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

4-[(Aminoiminomethyl)amino]benzoic acid 6-(aminoiminomethyl)-2-naphthalenyl ester dimethanesulfonate

CAS Number

82956-11-4

PubChem ID

54953

InChI Key

SRXKIZXIRHMPFW-UHFFFAOYSA-N

SMILES

CS(=O)(O)=O.NC(C1=CC=C2C(C=CC(OC(C3=CC=C(NC(N)=N)C=C3)=O)=C2)=C1)=N.CS(=O)(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 53.96 100
DMSO 53.96 100

Preparing Stock Solutions for Nafamostat mesylate

The following data is based on the product molecular weight 539.59

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.85 mL 9.27 mL 18.53 mL
5 mM 0.37 mL 1.85 mL 3.71 mL
10 mM 0.19 mL 0.93 mL 1.85 mL
50 mM 0.04 mL 0.19 mL 0.37 mL

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

x
=
x

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Product Documents for Nafamostat mesylate

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Nafamostat mesylate

For research use only

Privacy Policy
Cookie Policy
Site Map
© Copyright 2026 Bio-Techne. All Rights Reserved. All trademarks and registered trademarks are the property of Bio-Techne and its brands unless otherwise specified.