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Key Product Details
Description: | Potent GABAA agonist; also GABAA-ρ partial agonist |
Chemical Name: | 5-Aminomethyl-3-hydroxyisoxazole |
Purity: | ≥98% |
Molecular Weight: | 114.1 |
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Citations (45)
Citations are publications that use Bio-Techne products. Selected citations for Muscimol include:
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Kramer et al.
(2020)
Axonal mechanisms mediating γ-aminobutyric acid receptor type A (GABA-A) inhibition of striatal dopamine release.
ELife.
9
PMID: 32870779 -
Xiao et al.
(2018)
Septal and Hippocampal Neurons Contribute to Auditory Relay and Fear Conditioning.
Front Cell Neurosci.
12:102
PMID: 29713265 -
Namikawa et al.
(2018)
Salicylate-Induced Suppression of Electrically Driven Activity in Brain Slices from the Auditory Cortex of Aging Mice.
Front Aging Neurosci.
9:395
PMID: 29311894 -
Brodnik et al.
(2018)
Local GABAA receptor mediated suppression of DA release within the nucleus accumbens.
ACS Chem Neurosci.
17:1978
PMID: 30253088 -
Tian and Brainard
(2017)
Discrete Circuits Support Generalized versus Context-Specific Vocal Learning in the Songbird.
Neuron.
96:1168
PMID: 29154128 -
David-Pereira
(2017)
The medullary dorsal reticular nucleus as a relay for descending pronociception induced by the mGluR5 in the rat infralimbic cortex.
Neuroscience.
349:341
PMID: 28300633 -
Nasehi et al.
(2016)
Additive effect of harmane and muscimol for memory consolidation impairment in inhibitory avoidance task
Neuroscience.
339:287
PMID: 27725215 -
Chen et al.
(2016)
Honokiol suppresses TNF-α-induced neutrophil adhesion on cerebral endothelial cells by disrupting polyubiquitination and degradation of IκBα.
Nature.
6:26554
PMID: 27212040 -
Hengen et al.
(2015)
Daily isoflu. exposure increases barbiturate insensitivity in medullary respiratory and cortical neurons via expression of η-subunit containing GABA ARs.
PLoS One.
10:e0119351
PMID: 25748028 -
Grosso et al.
(2015)
The higher order auditory cortex is involved in the assignment of affective value to sensory stimuli.
Nat Commun.
6:8886
PMID: 26619940 -
Richardson and Shelton
(2015)
NMDA receptor channel blocker-like discriminative stimulus effects of NO gas.
Front Integr Neurosci.
352:156
PMID: 25368340 -
Parent et al.
(2015)
The medial prefrontal cortex is crucial for the maintenance of persistent licking and the expression of incentive contrast.
Neurobiol Dis.
9:23
PMID: 25870544 -
Sivakumaran et al.
(2015)
Selective inhibition of KCC2 leads to hyperexcitability and epileptiform discharges in hippocampal slices and in vivo.
EXCLI J.
35:8291
PMID: 26019342 -
Wang et al.
(2015)
Protein kinase C-dependent growth-associated protein 43 phosphorylation regulates gephyrin aggregation at developing GABAergic synapses.
J Neurosci.
35:1712
PMID: 25755278 -
Taylor-Burds et al.
(2015)
Chloride Accumulators NKCC1 and AE2 in Mouse GnRH Neurons: Implications for GABAA Mediated Excitation.
J Biol Chem.
10:e0131076
PMID: 26110920 -
Kangarlu-Haghighi et al.
(2015)
The effect of BLA GABA(A) receptors in anxiolytic-like effect and aversive memory deficit induced by ACPA.
Sci Rep.
14:613
PMID: 26648818 -
Arama et al.
(2015)
GABAA receptor activity shapes the formation of inhibitory synapses between developing medium spiny neurons.
PLoS One.
9:290
PMID: 26300728 -
Lee et al.
(2015)
Modulation of Spinal GABAergic Inhibition and Mechanical Hypersensitivity following Chronic Compression of Dorsal Root Ganglion in the Rat.
Neural Plast.
2015:924728
PMID: 26451259 -
Rubio et al.
(2015)
Context-induced reinstatement of methA. seeking is associated with unique molecular alterations in Fos-expressing dorsolateral striatum neurons.
J Neurosci.
35:5625
PMID: 25855177 -
Kirwan et al.
(2015)
Development and function of human cerebral cortex neural networks from pluripotent stem cells in vitro.
PLoS One.
142:3178
PMID: 26395144 -
Xia et al.
(2014)
Regulation of action potential waveforms by axonal GABAA receptors in cortical pyramidal neurons.
PLoS One.
9:e100968
PMID: 24971996 -
Shah et al.
(2014)
Pachymic Acid Enhances Drug-Induced Sleeping Behaviors via GABAA-ergic Systems in Mice.
Biomol Ther (Seoul).
22:314
PMID: 25143810 -
Tashiro et al.
(2014)
GABAergic influence on temporomandibular joint-responsive spinomedullary neurons depends on estrogen status.
Neurobiol Learn Mem.
259:53
PMID: 24316475 -
Pandya and Pillai
(2014)
TrkB interacts with ErbB4 and regulates NRG1-induced NR2B phosphorylation in cortical neurons before synaptogenesis.
Neuroscience.
12:47
PMID: 25052836 -
Zagha et al.
(2013)
Motor cortex feedback influences sensory processing by modulating network state.
Neuron.
79:567
PMID: 23850595 -
Maclaren et al.
(2013)
Updating of action-outcome associations is prevented by inactivation of the posterior pedunculopontine tegmental nucleus.
PLoS Comput Biol.
102:28
PMID: 23567109 -
Wagner et al.
(2013)
The dorsomedial hypothalamus mediates stress-induced hyperalgesia and is the source of the pronociceptive peptide cholecystokinin in the rostral ventromedial medulla.
Mol Cell Biol.
238:29
PMID: 23415792 -
Yang et al.
(2013)
PF inhibits superoxide production, elastase release, and chemotaxis in formyl peptide-activated human neutrophils by blocking formyl peptide receptor 1.
J Immunol.
190:6511
PMID: 23670191 -
Pouille et al.
(2013)
The contribution of synaptic location to inhibitory gain control in pyramidal cells.
Physiol Rep.
1:e00067
PMID: 24303159 -
Ring et al.
(2012)
GABA maintains the proliferation of progenitors in the developing chick ciliary marginal zone and non-pigmented ciliary epithelium.
PLoS One.
7:e36874
PMID: 22590629 -
Asiedu et al.
(2012)
Modulation of spinal GABAergic analgesia by inhibition of chloride extrusion capacity in mice.
J Pain.
13:546
PMID: 22537560 -
Lethbridge et al.
(2012)
Olfactory bulb glomerular NMDA receptors mediate olfactory nerve potentiation and odor preference learning in the neonate rat.
Front Cell Neurosci.
7:e35024
PMID: 22496886 -
Shulga et al.
(2012)
The loop diuretic compound blocks posttraumatic p75NTR upregulation and rescues injured neurons.
J Neurosci.
32:1757
PMID: 22302815 -
Ilie et al.
(2012)
Adenosine release during seizures attenuates GABAA receptor-mediated depolarization.
J Neurosci.
32:5321
PMID: 22496577 -
Wei et al.
(2011)
Development of asymmetric inhibition underlying direction selectivity in the retina.
J Biol Chem.
469:402
PMID: 21131947 -
Porcher et al.
(2011)
Positive feedback regulation between γ-aminobutyric acid type A (GABA(A)) receptor signaling and brain-derived neurotrophic factor (BDNF) release in developing neurons.
Neuroscience.
286:21667
PMID: 21474450 -
Doyon et al.
(2011)
Efficacy of synaptic inhibition depends on multiple, dynamically interacting mechanisms implicated in chloride homeostasis.
J Pharmacol Exp Ther.
7:e1002149
PMID: 21931544 -
Santhakumar et al.
(2010)
Developmental regulation and neuroprotective effects of striatal tonic GABAA currents.
Development.
167:644
PMID: 20206233 -
Yoon et al.
(2009)
Intrathecal injection of the neurosteroid, DHEAS, produces mechanical allodynia in mice: involvement of spinal sigma-1 and GABA receptors.
Br J Pharmacol.
157:666
PMID: 19422393 -
Kalmbach et al.
(2009)
Interactions between prefrontal cortex and cerebellum revealed by trace eyelid conditioning.
Learn Mem.
16:86
PMID: 19144967 -
Long et al.
(2009)
Nerve Terminal GABAA Receptors Activate Ca2+/Calmodulin-dependent Signaling to Inhibit Voltage-gated Ca2+ Influx and Glutamate Release.
Neuroscience.
284:8726
PMID: 19141616 -
Manookin et al.
(2008)
Disinhibition combines with excitation to extend the operating range of the OFF visual pathway in daylight.
J Neurosci.
28:4136
PMID: 18417693 -
Miyazato et al.
(2008)
GABA receptor activation in the lumbosacral spinal cord decreases detrusor overactivity in spinal cord injured rats.
J Urol.
179:1178
PMID: 18206170 -
Milenković et al.
(2007)
Development of chloride-mediated inhibition in neurons of the anteroventral cochlear nucleus of gerbil (Meriones unguiculatus).
J Neurophysiol.
98:1634
PMID: 17596413 -
Piqueras and Martínez
(2004)
Peripheral GABAB agonists stimulate gastric acid secretion in mice.
Br J Pharmacol.
142:1038
PMID: 15210585
There are no citations that match your criteria.