MRT 68601 hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 5067

Potent TBK inhibitor
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Key Product Details

Description

Potent TBK inhibitor

View all TANK Binding Kinase Inhibitors »

Product Description

MRT 68601 hydrochloride is a potent TBK1 (TANK-binding kinase-1) inhibitor (IC50 = 6 nM). Inhibits the formation of autophagosomes in lung cancer cells.

Product Specifications

Molecular Weight

487.04

Formula

C25H34N6O2.HCl

Storage

Desiccate at RT

Purity

≥98% (HPLC)

Chemical Name

N-[3-[[5-Cyclopropyl-2-[[4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide hydrochloride

CAS Number

1962928-25-1

PubChem ID

121513855

InChI Key

BOBHGYDEKISHIZ-UHFFFAOYSA-N

SMILES

O=C(C1CCC1)NCCCNC2=C(C3CC3)C=NC(NC4=CC=C(N5CCOCC5)C=C4)=N2.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 48.7 100
DMSO 48.7 100

Preparing Stock Solutions for MRT 68601 hydrochloride

The following data is based on the product molecular weight 487.04

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.05 mL 10.27 mL 20.53 mL
5 mM 0.41 mL 2.05 mL 4.11 mL
10 mM 0.21 mL 1.03 mL 2.05 mL
50 mM 0.04 mL 0.21 mL 0.41 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for MRT 68601 hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for MRT 68601 hydrochloride

For research use only

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