MRS 2905
Tocris Bioscience, part of Bio-Techne | Catalog # 5633
Potent and selective P2Y14 receptor agonist
Key Product Details
Description
Potent and selective P2Y14 receptor agonist
Product Description
MRS 2905 is a potent and selective P2Y14 receptor agonist (EC50 = 0.92 nM). Exhibits >2000-fold selectivity over P2Y6.Product Specifications
Molecular Weight
484.20
Formula
C10H13N2Na3O10P2S
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
2-Thiouridine-5'-O-(α, β-methylene)diphosphate trisodium salt
CAS Number
3033550-04-5
PubChem ID
121513874
InChI Key
YLWNGINRXVXFAA-ZXSRDNBLSA-K
SMILES
O[C@H]1[C@H](O)[C@H](N2C(NC(C=C2)=O)=S)O[C@@H]1COP(CP(O[Na])(O[Na])=O)(O[Na])=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 21.79 | 45 |
Preparing Stock Solutions
for MRS 2905
The following data is based on the product molecular weight 484.20
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.45 mM | 4.59 mL | 22.95 mL | 45.89 mL |
| 2.25 mM | 0.92 mL | 4.59 mL | 9.18 mL |
| 4.5 mM | 0.46 mL | 2.29 mL | 4.59 mL |
| 22.5 mM | 0.09 mL | 0.46 mL | 0.92 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Lazarowski UDP-sugars as extracellular signaling molecules: cellular and physiologic consequences of P2Y14 receptor activation. Mol.Pharmacol. 2015 PMID: 25829059
- Das Human P2Y14 receptor agonists: truncation of the hexose moiety of uridine-5'-diphosphoglucose and its replacement with alkyl and aryl groups J.Med.Chem. 2010 PMID: 19902968
Product Specific Notices for MRS 2905
For research use only
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