MRS 2768 tetrasodium salt
Tocris Bioscience, part of Bio-Techne | Catalog # 3884
Selective P2Y2 agonist
Product Description
MRS 2768 tetrasodium salt is a selective P2Y2 agonist (EC50 = 1.89 μM). Displays no affinity for human P2Y4 or P2Y6 receptors. In a mouse model of myocardial infarction, pre-treatment with MRS 2768 protects cardiocytes and heart tissue from ischemic damage, and reduces circulating levels of TNF-α.Product Specifications
Molecular Weight
728.14
Formula
C15H16N2O18P4Na4
Storage
Store at -80°C
Purity
≥98% (HPLC)
Chemical Name
Uridine-5'-tetraphosphate δ-phenyl ester tetrasodium salt
CAS Number
2567869-47-8
PubChem ID
90488893
InChI Key
ASYFBNZFGLWLNC-YYXHNCPRSA-J
SMILES
[Na+].[Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])(=O)OP([O-])(=O)OP([O-])(=O)OC1=CC=CC=C1)N1C=CC(=O)NC1=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble in water (supplied pre-dissolved at a concentration of 10mM) |
Calculators
Molarity Calculator
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Background References
References are publications that support the biological activity of the product.
- Hochhauser P2Y2 receptor agonist with enhanced stability protects the heart from ischemic damage in vitro and in vivo. Purinergic Signal. 2013 PMID: 23828651
- Ko Synthesis and potency of novel uracil nucleotides and derivatives as P2Y2 and P2Y6 receptor agonists. Bioorg.Med.Chem. 2008 PMID: 18514530
Product Specific Notices for MRS 2768 tetrasodium salt
For research use only
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