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MRS 2578

Tocris Bioscience a Bio-Techne Brand

P2Y Receptor Antagonists Small Molecule
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Key Product Details

Description: Selective P2Y6 antagonist
Chemical Name: N,N''-1,4-Butanediylbis[N'-(3-isothiocyanatophenyl)thiourea
Purity: ≥95% (HPLC)
Molecular Weight: 472.66

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Citations for MRS 2578 (24)

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Customer Reviews for MRS 2578 (2)

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  • Good inhibitor
    Name: Anonymous
    Species: Mouse
    Assay Type: In Vivo
    Cell Line/Tissue: phagocyte
    DMSO dilution 10 μM
    MRS 2578 Serum 2146
  • MRS 2578 inhibits LPS-induced inflammation
    Name: Anonymous
    Species: Mouse
    Assay Type: In Vitro
    Cell Line/Tissue: Macrophages
    RAW macrophages were stimulated with LPS (200 ng/ml) in the absence or presence of A 804598 (1 μM) or MRS 2578 (100 μM) for 8 h to follow iNOS expression by qPCR. Both compounds inhibited LPS-induced iNOS expression revealing role of purinergic receptors.
    MRS 2578 Serum 2146

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Product Documents for MRS 2578

Certificate of Analysis

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