MRS 2500 tetraammonium salt
Catalog # 2159 | Tocris Bioscience a Bio-Techne Brand
Highly potent and selective P2Y1 antagonist
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Key Product Details
Description: | Highly potent and selective P2Y1 antagonist |
Chemical Name: | (1R*,2S*)-4-[2-Iodo-6-(methylamino)-9H-purin-9-yl]-2-(phosphonooxy)bicyclo[3.1.0]hexane-1-methanol dihydrogen phosphate ester tetraammonium salt |
Purity: | ≥96% (HPLC) |
Molecular Weight: | 629.29 |
Citations for MRS 2500 tetraammonium salt (22)
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Citations are publications that use Bio-Techne products. Selected citations for MRS 2500 tetraammonium salt include:
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Babola et al.
(2021)
Purinergic signaling controls spontaneous activity in the auditory system throughout early development.
J.Neurosci..
41:594
PMID: 33303678 -
Babola et al.
(2020)
Purinergic signaling in cochlear supporting cells reduces hair cell excitability by increasing the extracellular space.
Elife.
9:e52160
PMID: 31913121 -
Dosch et al.
(2019)
Connexin-43-dependent ATP release mediates macrophage activation during sepsis.
Elife.
8
PMID: 30735126 -
Liu et al.
(2018)
Salvianolic acids from antithrombotic Traditional Chinese Medicine Danshen are antagonists of human P2Y1 and P2Y12 receptors.
Sci Rep.
8(1):11380
PMID: 30038283 -
Ryu et al.
(2017)
Paradoxical induction of growth arrest and apoptosis by EGF via the up-regulation of PTEN by activating Redox factor-1/Egr-1 in human lung cancer cells.
Oncotarget.
8:4181
PMID: 27935858 -
Baron et al.
(2015)
The NLRP3 inflammasome is activated by nanoparticles through ATP, ADP and adenosine.
Thromb J.
6:e1629
PMID: 25654762 -
Braganhol et al.
(2015)
Nucleotide receptors control IL-8/CXCL8 and MCP-1/CCL2 secretions as well as proliferation in human glioma cells.
Biochim Biophys Acta.
1852:120
PMID: 25445541 -
Erdélyi et al.
(2014)
Analyzing receptor assemblies in the cell membrane using fluorescence anisotropy imaging with TIRF microscopy.
PLoS One.
9:e100526
PMID: 24945870 -
Kurahashi et al.
(2014)
Platelet-derived growth factor receptor-α-positive cells and not smooth muscle cells mediate purinergic hyperpolarization in murine colonic muscles.
Am J Physiol Cell Physiol.
307:C561
PMID: 25055825 -
Ilatovskaya et al.
(2013)
Pharmacological characterization of the P2 receptors profile in the podocytes of the freshly isolated rat glomeruli.
Am J Physiol Cell Physiol.
305:C1050
PMID: 24048730 -
Alefishat et al.
(2013)
Antagonism of P2Y1-induced vasorelaxation by acyl CoA: a critical role for palmitate and 3'-phosphate.
Br J Pharmacol.
168:1911
PMID: 23215951 -
Fei et al.
(2013)
Neurogenic mucosal bicarbonate secretion in guinea pig duodenum.
Br J Pharmacol.
168:880
PMID: 22994306 -
Helms et al.
(2013)
Mechanisms of hemolysis-associated platelet activation.
J Thromb Haemost.
11:2148
PMID: 24119131 -
Gao et al.
(2013)
The role of P2Y(14) and other P2Y receptors in degranulation of human LAD2 mast cells.
J Pharmacol Exp Ther.
9:31
PMID: 22825617 -
Duffy et al.
(2012)
Changes in neuromuscular transmission in the W/W(v) mouse internal anal sphincter.
Neurogastroenterol Motil.
24:e41
PMID: 22074497 -
Hwang et al.
(2011)
β-nicotinamide adenine dinucleotide is an enteric inhibitory neurotransmitter in human and nonhuman primate colons.
Gastroenterology.
140:608
PMID: 20875415 -
Gorman et al.
(2010)
Adenine nucleotide control of coronary blood flow during exercise.
Am J Physiol Heart Circ Physiol.
299:H1981
PMID: 20852039 -
Ham et al.
(2010)
Endogenous luminal surface adenosine signaling regulates duodenal bicarbonate secretion in rats.
J Cell Biochem.
335:607
PMID: 20805305 -
Bradley et al.
(2010)
Novel excitatory effects of adenosine triphosphate on contractile and pacemaker activity in rabbit urethral smooth muscle.
J Urol.
183:801
PMID: 20022059 -
Konopatskaya et al.
(2009)
PKCalpha regulates platelet granule secretion and thrombus formation in mice.
J Clin Invest.
119:399
PMID: 19147982 -
Högberg et al.
(2009)
Mild hypothermia does not attenuate platelet aggregation and may even increase ADP-stimulated platelet aggregation after clopid. treatment.
Purinergic Signal.
7:2
PMID: 19236702 -
Ohtani et al.
(2008)
Evidence for the possible involvement of the P2Y(6) receptor in Ca (2+) mobilization and Ins secretion in mouse pancreatic islets.
Purinergic Signal.
4:365
PMID: 18784987
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