MRS 2211
Tocris Bioscience, part of Bio-Techne | Catalog # 2402
Competitive P2Y13 antagonist
Product Description
MRS 2211 is a competitive P2Y13 receptor antagonist (pIC50 = 5.97) that displays > 20-fold selectivity over P2Y1 and P2Y12 receptors.Product Specifications
Molecular Weight
474.66
Formula
C14H10N4O8Na2PCl
Storage
Desiccate at -20°C
Purity
≥96% (HPLC)
Chemical Name
2-[(2-Chloro-5-nitrophenyl)azo]-5-hydroxy-6-methyl-3-[(phosphonooxy)methyl]-4-pyridinecarboxaldehyde disodium salt
PubChem ID
57369297
InChI Key
VLNWYJFCKRYEJA-QIKYXUGXSA-L
SMILES
[Na+].[Na+].CC1=C(O)C(C=O)=C(COP([O-])([O-])=O)C(\N=N\C2=C(Cl)C=CC(=C2)[N+]([O-])=O)=N1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 33.23 | 70 |
Preparing Stock Solutions
for MRS 2211
The following data is based on the product molecular weight 474.66
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.7 mM | 3.01 mL | 15.05 mL | 30.10 mL |
| 3.5 mM | 0.60 mL | 3.01 mL | 6.02 mL |
| 7 mM | 0.30 mL | 1.50 mL | 3.01 mL |
| 35 mM | 0.06 mL | 0.30 mL | 0.60 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Kugelgen Pharmacological profiles of cloned mammalian P2Y-receptor subtypes. Pharmacol.Ther. 2006 PMID: 16257449
- Kim Synthesis of pyridoxal phosphate derivatives with antagonist activity at the P2Y13 receptor. Biochem.Pharmacol. 2005 PMID: 15913566
Product Specific Notices for MRS 2211
For research use only
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