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Modafinil

Tocris Bioscience, part of Bio-Techne | Catalog # 1811

Psychostimulant
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1811/50
1811/10

Key Product Details

Description

Psychostimulant

Alternative Names

CRL 40476

Product Description

Modafinil is a psychostimulant that displays neuroprotective and antiparkinsonian activity in a primate model of Parkinson's disease. Modafinil promotes vigilance and wakefulness without the central and peripheral side effects associated with conventional dopaminergic psychostimulants. Mechanism of action is not fully understood, possibly via modulation of catecholamine/GABAergic neurotransmission.

Product Specifications

Molecular Weight

273.35

Formula

C15H15NO2S

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

2-[(Diphenylmethyl)sulfinyl]acetamide

CAS Number

68693-11-8

PubChem ID

4236

InChI Key

YFGHCGITMMYXAQ-UHFFFAOYSA-N

SMILES

O=S(CC(N)=O)C(C2=CC=CC=C2)C1=CC=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 20.5 75
Ethanol 2.73 10

Preparing Stock Solutions for Modafinil

The following data is based on the product molecular weight 273.35

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.75 mM 4.88 mL 24.39 mL 48.78 mL
3.75 mM 0.98 mL 4.88 mL 9.76 mL
7.5 mM 0.49 mL 2.44 mL 4.88 mL
37.5 mM 0.10 mL 0.49 mL 0.98 mL

Calculators

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

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Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background References

References are publications that support the biological activity of the product.

Product Documents for Modafinil

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Modafinil

For research use only

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