MK 1903

Tocris Bioscience, part of Bio-Techne | Catalog # 4622

Potent and selective GPR109A (HCA2) agonist
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Key Product Details

Description

Potent and selective GPR109A (HCA2) agonist

View all Nicotinic Acid Receptor (GPR109) Agonists »

Product Description

MK 1903 is a potent and selective hydroxycarboxylic acid receptor 2 (HCA2, GPR109A) full agonist; exhibits greater potency than niacin in a whole cell HTRF-cAMP assay (EC50 values are 12.9 and 51 nM respectively). Exhibits no binding at the GRP109B receptor.

Product Specifications

Molecular Weight

164.16

Formula

C8H8N2O2

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

(4aR,5aR)-4,4a,5,5a-Tetrahydro-1H-cyclopropa[4,5]cyclopenta[1,2]pyrazole-3-carboxylic acid

CAS Number

1268882-43-4

PubChem ID

49763030

InChI Key

CUTZNERBKDMLAP-QWWZWVQMSA-N

SMILES

[H][C@@]12CC3=C(NN=C3C(O)=O)[C@@]([H])1C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 16.42 100
Ethanol 8.21 50

Preparing Stock Solutions for MK 1903

The following data is based on the product molecular weight 164.16

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 6.09 mL 30.46 mL 60.92 mL
5 mM 1.22 mL 6.09 mL 12.18 mL
10 mM 0.61 mL 3.05 mL 6.09 mL
50 mM 0.12 mL 0.61 mL 1.22 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for MK 1903

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for MK 1903

For research use only

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