MitoBoronic acid

Tocris Bioscience, part of Bio-Techne | Catalog # 7949

Ratiometric mass spectrometry mitochondrial hydrogen peroxide (H2O2) probe
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Key Product Details

Description

Ratiometric mass spectrometry mitochondrial hydrogen peroxide (H2O2) probe

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Product Description

MitoBoronic acid (MitoB) is a ratiometric mass spectrometry mitochondrial hydrogen peroxide (H2O2) probe. MitoBoronic acid is taken up into cells and accumulates inside the mitochondrial matrix where it reacts to H2O2 to be converted in MitoP. Measurement of MitoB/MitoP ratio by liquid chromatography tandem mass spectrometry (LC-MS/MS) is an indicator of the mitochondrial matrix H2O2 concentration. This method can be used in vitro and in vivo.

Product Specifications

Molecular Weight

477.14

Formula

C25H23BBrO2P

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

[(3-Boronophenyl)methyl]triphenylphosphonium bromide

CAS Number

1247025-84-8

PubChem ID

91885451

InChI Key

VDNRROALFUZCBO-UHFFFAOYSA-M

SMILES

OB(C1=CC=CC(C[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)=C1)O.[Br-]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 47.71 100
Ethanol 23.86 50 with gentle warming

Preparing Stock Solutions for MitoBoronic acid

The following data is based on the product molecular weight 477.14

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.10 mL 10.48 mL 20.96 mL
5 mM 0.42 mL 2.10 mL 4.19 mL
10 mM 0.21 mL 1.05 mL 2.10 mL
50 mM 0.04 mL 0.21 mL 0.42 mL

Calculators

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Product Documents for MitoBoronic acid

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for MitoBoronic acid

For research use only

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