(-)-Quinpirole hydrochloride
Tocris Bioscience, part of Bio-Techne | Catalog # 1061
Selective D2-like agonist
Key Product Details
Description
Selective D2-like agonist
Product Description
(-)-Quinpirole hydrochloride is a selective dopamine D2 receptor agonist (Ki values are 4.8, ~24, ~30 and 1900 nM at D2, D3, D4 and D1 receptors respectively).Licensing Information
Sold with the permission of Eli Lilly and CompanyProduct Specifications
Molecular Weight
255.79
Formula
C13H21N3.HCl
Storage
Desiccate at -20°C
Purity
≥98% (HPLC)
Chemical Name
(4aR-trans)-4,4a,5,6,7,8,8a,9-Octahydro-5-propyl-1H-pyrazolo[3,4-g]quinoline hydrochloride
CAS Number
85798-08-9
PubChem ID
55397
InChI Key
HJHVRVJTYPKTHX-HTMVYDOJSA-N
SMILES
Cl.[H][C@]12CCCN(CCC)[C@]1([H])CC1=CNN=C1C2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 25.58 | 100 | |
| DMSO | 6.39 | 25 |
Preparing Stock Solutions
for (-)-Quinpirole hydrochloride
The following data is based on the product molecular weight 255.79
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.91 mL | 19.55 mL | 39.09 mL |
| 5 mM | 0.78 mL | 3.91 mL | 7.82 mL |
| 10 mM | 0.39 mL | 1.95 mL | 3.91 mL |
| 50 mM | 0.08 mL | 0.39 mL | 0.78 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Seeman and Van Tol DA receptor pharmacology. Trends Pharmacol.Sci. 1994 PMID: 7940991
- Sullivan Effects of quinpirole on central DA systems in sensitized and non-sensitized rats. Neuroscience 1998 PMID: 9483561
- Levant Modulation of [3H]quinpirole binding in brain by monoamine oxidase inhibitors: evidence for a potential novel binding site. J.Pharmacol.Exp.Ther. 1996 PMID: 8764345
Product Specific Notices for (-)-Quinpirole hydrochloride
For research use only
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