Melatonin
Tocris Bioscience, part of Bio-Techne | Catalog # 3550
Endogenous hormone; agonist at MT1 and MT2
Key Product Details
Description
Endogenous hormone; agonist at MT1 and MT2
Product Description
Melatonin is an endogenous hormone that acts as an agonist at melatonin receptors MT1 and MT2. Exhibits a prominent role in the control of circadian rhythm, displays immunomodulatory activity and acts as a powerful antioxidant in vivo.Product Specifications
Molecular Weight
232.28
Formula
C13H16N2O2
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
N-Acetyl-5-methoxytryptamine
CAS Number
73-31-4
PubChem ID
896
InChI Key
DRLFMBDRBRZALE-UHFFFAOYSA-N
SMILES
O=C(C)NCCC2=CNC1=CC=C(OC)C=C12
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 11.61 | 50 |
Preparing Stock Solutions
for Melatonin
The following data is based on the product molecular weight 232.28
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.5 mM | 8.61 mL | 43.05 mL | 86.10 mL |
| 2.5 mM | 1.72 mL | 8.61 mL | 17.22 mL |
| 5 mM | 0.86 mL | 4.31 mL | 8.61 mL |
| 25 mM | 0.17 mL | 0.86 mL | 1.72 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Fischer Melatonin as a major skin protectant: from free radical scavenging to DNA damage repair. Exp.Dermatol. 2008 PMID: 18643846
- Cardinali Melatonin and melatonergic drugs on sleep: possible mechanisms of action. Int.J.Neurosci. 2009 PMID: 19326288
- Bubenik Thirty four years since the discovery of gastrointestinal melatonin. J.Physiol.Pharmacol. 2008 PMID: 18812627
Product Specific Notices for Melatonin
For research use only
Loading...
Loading...
Loading...