MeBIO

Tocris Bioscience, part of Bio-Techne | Catalog # 3873

Inactive analog of BIO (Cat. No. 3194)
Discontinued Product
3873 has been discontinued. View all GSK-3 Inhibitors products.

Key Product Details

Description

Inactive analog of BIO (Cat. No. 3194)

View all GSK-3 Inhibitors »

Product Description

MeBIO is a control analog of 6-bromoindirubin-3'-oxime (BIO). Displays minimal activity against CDK1/Cyclin B, GSK-3 α/β, and CDK5/p25 (IC50 values are 92.0, 44-100 and >100 μM respectively). Aryl hydrocarbon receptor (AhR) agonist; causes redistribution of AhR to the nucleus.

Active Analog also available.

Product Specifications

Molecular Weight

370.20

Formula

C17H12BrN3O2

Storage

Store at +4°C

Purity

≥99% (HPLC)

Chemical Name

(2'Z,3'E)-6-Bromo-1-methylindirubin-3'-oxime

CAS Number

667463-95-8

PubChem ID

24906281

InChI Key

WWVVQXIBSZPELF-UHFFFAOYSA-N

SMILES

O/N=C(C1=CC=CC=C1N2)/C2=C3/C(N(C)C4=C3C=CC(Br)=C4)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 3.7 10

Preparing Stock Solutions for MeBIO

The following data is based on the product molecular weight 370.20

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.01 mL 135.06 mL 270.12 mL
0.5 mM 5.40 mL 27.01 mL 54.02 mL
1 mM 2.70 mL 13.51 mL 27.01 mL
5 mM 0.54 mL 2.70 mL 5.40 mL

Calculators

Molarity Calculator

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Dilution Calculator

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for MeBIO

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for MeBIO

For research use only

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