MCH (human, mouse, rat)

Name: MCH (human, mouse, rat)
Brand: Tocris Bioscience
SKU: 3806

Tocris Bioscience, part of Bio-Techne | Catalog # 3806

Citations (10)

COA / SDS

Potent endogenous MCH agonist

Key Product Details

Description:	Potent endogenous MCH agonist
Alternative Names:	Melanin-concentrating hormone (human,mouse,rat)
Purity:	≥95% (HPLC)
Molecular Weight:	2386.84

View Full Technical Details for MCH (human, mouse, rat)

Technical Data
Citations

Biological Activity for MCH (human, mouse, rat)

MCH (human, mouse, rat) is a potent endogenous agonist at melanin-concentration hormone (MCH) receptors (IC₅₀ values are 0.3 and 1.5 nM and EC₅₀ values are 3.9 and 0.1 nM at MCH₁ and MCH₂ receptors respectively). Increases food intake in vivo.

Technical Data for MCH (human, mouse, rat)

M. Wt	2386.84
Formula	C₁₀₅H₁₆₀N₃₀O₂₆S₄
Single Letter Sequence	DFDMLRCMLGRVYRPCWQV (Modification: Disulfide bridge: 7-16)
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	128315-56-0
PubChem ID	24868207
InChi Key	MWLPXSMFEPHETN-QRXCLJFASA-N
Smiles	[H]N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC2=CC=C(O)C=C2)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCSC)NC1=O)C(C)C)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C(C)C)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for MCH (human, mouse, rat)

Solubility

Soluble to 1mg/ml in water

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References for MCH (human, mouse, rat)

References are publications that support the biological activity of the product.

Sailer Identification and characterization of a second melanin-concentrating hormone receptor, MCH-2R. Proc.Natl.Acad.Sci.USA