M617
Tocris Bioscience, part of Bio-Techne | Catalog # 2697
Selective GAL1 agonist
Key Product Details
Description
Selective GAL1 agonist
Alternative Names
Galanin(1-13)-Gln14-bradykinin(2-9)amide
Product Description
M617 is a selective galanin GAL1 receptor agonist (Ki values are 0.23 and 5.71 nM for GAL1 and GAL2 receptors respectively). Enhances food consumption in rats following i.c.v. administration and reduces CAP-induced inflammatory pain.Product Specifications
Molecular Weight
2361.68
Formula
C112H161N29O28
Storage
Store at -20°C
Purity
≥95% (HPLC)
CAS Number
860790-38-1
PubChem ID
16158157
InChI Key
PAYBRARNTYCYOT-OTTBQUPZSA-N
SMILES
[H]NCC(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 1mg/ml in water |
Calculators
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Background References
References are publications that support the biological activity of the product.
- Jimenez-Andrade Activation of peripheral galanin receptors: differential effects on nociception. Pharmacol.Biochem.Behav. 2006 PMID: 16996122
- Lundstrom A galanin receptor subtype 1 specific agonist. Int.J.Pept.Res.Ther.
- Mazarati Regulation of kindling epileptogenesis by hippocampal galanin type 1 and type 2 receptors: the effects of subtype-selective agonists and the role of G-protein-mediated signaling. J.Pharmacol.Exp.Ther. 2006 PMID: 16699066
Product Specific Notices for M617
For research use only
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