M 084 hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 5807

TRPC4 and TRPC5 inhibitor; antidepressant and anxiolytic
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Key Product Details

Description

TRPC4 and TRPC5 inhibitor; antidepressant and anxiolytic

View all TRPC Channel Inhibitors »

Product Description

M 084 hydrochloride is a TRPC4/5 channel blocker (IC50 values are 3.7-10.3 and 8.2 μM, respectively). Also weakly blocks TRPC3 channels. Exhibits rapid antidepressant and anxiolytic effects in vivo.

Product Specifications

Molecular Weight

225.72

Formula

C11H15N3.HCl

Storage

Desiccate at RT

Purity

≥99% (HPLC)

Chemical Name

N-Butyl-1H-benzimidazol-2-amine hydrochloride

CAS Number

1992047-63-8

PubChem ID

121513894

InChI Key

DMLSYUAQEOLJQC-UHFFFAOYSA-N

SMILES

CCCCNC1=NC2=CC=CC=C2N1.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 22.57 100
DMSO 22.57 100

Preparing Stock Solutions for M 084 hydrochloride

The following data is based on the product molecular weight 225.72

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.43 mL 22.15 mL 44.30 mL
5 mM 0.89 mL 4.43 mL 8.86 mL
10 mM 0.44 mL 2.22 mL 4.43 mL
50 mM 0.09 mL 0.44 mL 0.89 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for M 084 hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for M 084 hydrochloride

For research use only

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