LY 3502970

Tocris Bioscience, part of Bio-Techne | Catalog # 9037

Non-peptide GLP-1 receptor agonist
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Key Product Details

Description

Non-peptide GLP-1 receptor agonist

Alternative Names

OWL833,GLP-1 receptor agonist 1

View all Glucagon-Like Peptide 1 Receptor Agonists »

Product Description

LY 3502970 is a potent and selective non-peptide GLP-1 receptor agonist, biased towards G protein activation and no β-arrestin recruitment. Induces glucose lowering in humanized GLP-1R transgenic mice and insulinotropic and hypophagic effects. Orally bioavailable.

Product Specifications

Molecular Weight

882.97

Formula

C48H48F2N10O5

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

3-[(1S,2S)-1-[2-[[(4S)-2-(4-Fluoro-3,5-dimethylphenyl)-3-[3-(4-fluoro-1-methyl-1H-indazol-5-yl)-2,3-dihydro-2-oxo-1H-imidazol-1-yl]-2,4,6,7-tetrahydro-4-methyl-5H-pyrazolo[4,3-c]pyridin-5-yl]carbonyl]-5-[(4S)-tetrahydro-2,2-dimethyl-2H-pyran-4-yl]-1H-indol-1-yl]-2-methylcyclopropyl]-1,2,4-oxadiazol-5(2H)-one

CAS Number

2212020-52-3

PubChem ID

137319706

InChI Key

USUWIEBBBWHKNI-KHIFEHGGSA-N

SMILES

O=C(C1=CC2=CC([C@@H]3CC(OCC3)(C)C)=CC=C2N1[C@]4(C[C@@H]4C)C(N5)=NOC5=O)N6[C@@H](C)C7=C(N(N=C7CC6)C8=CC(C)=C(F)C(C)=C8)N9C=CN(C%10=CC=C%11N(C)N=CC%11=C%10F)C9=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 88.3 100

Preparing Stock Solutions for LY 3502970

The following data is based on the product molecular weight 882.97

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.13 mL 5.66 mL 11.33 mL
5 mM 0.23 mL 1.13 mL 2.27 mL
10 mM 0.11 mL 0.57 mL 1.13 mL
50 mM 0.02 mL 0.11 mL 0.23 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for LY 3502970

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for LY 3502970

For research use only

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