Luzindole
Tocris Bioscience, part of Bio-Techne | Catalog # 0877
Competitive melatonin MT1/MT2 antagonist
Key Product Details
Description
Competitive melatonin MT1/MT2 antagonist
Product Description
Luzindole is a melatonin antagonist.Product Specifications
Molecular Weight
292.38
Formula
C19H20N2O
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
N-Acetyl-2-benzyltryptamine
CAS Number
117946-91-5
PubChem ID
122162
InChI Key
WVVXBPKOIZGVNS-UHFFFAOYSA-N
SMILES
CC(=O)NCCC1=C(CC2=CC=CC=C2)NC2=CC=CC=C12
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 29.24 | 100 | |
| Ethanol | 29.24 | 100 |
Preparing Stock Solutions
for Luzindole
The following data is based on the product molecular weight 292.38
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.42 mL | 17.10 mL | 34.20 mL |
| 5 mM | 0.68 mL | 3.42 mL | 6.84 mL |
| 10 mM | 0.34 mL | 1.71 mL | 3.42 mL |
| 50 mM | 0.07 mL | 0.34 mL | 0.68 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Dubocovich Anti-depressant-like activity of the melatonin receptor antagonist, luzindole (N-0774), in mouse behavioural despair test. Eur.J.Pharmacol. 1990 PMID: 2168835
- Dubocovich Melatonin receptors: are there multiple subtypes? TiPS 1995 PMID: 7762083
- Dubocovich Luzindole (N-0774): a novel melatonin receptor antagonist. J.Pharmacol.Exp.Ther. 1988 PMID: 2843633
Product Specific Notices for Luzindole
For research use only
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