Leukotriene B4
Tocris Bioscience, part of Bio-Techne | Catalog # 2307
BLT1/BLT2 receptor agonist and potent chemotactic factor
Key Product Details
Description
BLT1/BLT2 receptor agonist and potent chemotactic factor
Alternative Names
LTB4,5,12-DiHETE
Product Description
Leukotriene B4 is a potent lipid inflammatory mediator derived from the 5-lipoxygenase pathway of arachidonic acid metabolism. Binds to BLT1 and BLT2 receptors and acts as a potent chemotactic agent and activator of leukocytes. Also displays antiviral activity towards DNA viruses and retroviruses.Product Specifications
Molecular Weight
336.47
Formula
C20H32O4
Storage
Store at -20°C
Purity
≥95% (HPLC)
Chemical Name
(5S,6Z,8E,10E,12R,14Z)-5,12-Dihydroxy-6,8,10,14-eicosatetraenoic acid
CAS Number
71160-24-2
PubChem ID
5280492
InChI Key
VNYSSYRCGWBHLG-AMOLWHMGSA-N
SMILES
O[C@@H](CCCC(O)=O)\C=C/C=C/C=C/[C@H](O)C/C=C\CCCCC
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble in ethanol (supplied pre-dissolved in anhydrous ethanol, 50µg/ml) |
Calculators
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Background References
References are publications that support the biological activity of the product.
- Ford-Hutchinson Leukotriene B4 in inflammation. Crit.Rev.Immunol. 1990 PMID: 2155000
- Yokomitso Leukotriene B4: metabolism and signal transduction. Arch.Biochem.Biophys. 2001 PMID: 11368003
- Bray Leukotriene B4: an inflammatory mediator in vivo. Prostaglandins 1981 PMID: 6270742
Product Specific Notices for Leukotriene B4
For research use only
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