[Leu5]-Enkephalin
Tocris Bioscience, part of Bio-Techne | Catalog # 1889
Endogenous opioid agonist peptide
Key Product Details
Description
Endogenous opioid agonist peptide
Alternative Names
ICI 114740,Dynorphin-(1-5),YGGFL
Product Description
[Leu5]-Enkephalin is an endogenous opioid agonist peptide; inhibits electrically stimulated contractions in mouse vas deferens (IC50 = 11.4 nM). Short-acting in vivo.Product Specifications
Molecular Weight
555.63
Formula
C28H37N5O7
Storage
Store at -20°C
Purity
≥95% (HPLC)
CAS Number
58822-25-6
PubChem ID
461776
InChI Key
URLZCHNOLZSCCA-VABKMULXSA-N
SMILES
[H]N[C@@H](CC1=CC=C(O)C=C1)C(=O)NCC(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 1mg/ml in water |
Calculators
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Background References
References are publications that support the biological activity of the product.
- Law and Loh 3H-Leu5-enkephalin specific binding to synaptic membrane - comparison with 3H-dihydromorphine and 3H-naloxone. Res.Commun.Chem.Pathol.Pharmacol. 1978 PMID: 705021
- Meunier Binding of Leu5-enkephalin and Met5-enkephalin to a particulate fraction from rat cerebrum. FEBS Lett. 1977 PMID: 862920
- DiMaio Synthesis and pharmacological characterization in vitro of cyclic enkephalin analogues: effect of conformational constraints on opiate receptor selectivity. J.Med.Chem. 1982 PMID: 6296388
Product Specific Notices for [Leu5]-Enkephalin
For research use only
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