Lenalidomide 5'-piperazine-7'-methoxy

Tocris Bioscience, part of Bio-Techne | Catalog # 8848

Cereblon ligand with terminal piperazine for onward chemistry
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Key Product Details

Description

Cereblon ligand with terminal piperazine for onward chemistry

View all Cereblon Ligands plus Linker Building Blocks »

Product Description

Lenalidomide 5'-piperazine-7'-methoxy is a functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand with a terminal piperazine for onward chemistry to generate Protein Degraders with rigid linkers. Part of a range of functionalized tool molecules for PROTAC R&D.

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Product Specifications

Molecular Weight

394.86

Formula

C18H22N4O4.HCl

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

3-(7-Methoxy-1-oxo-5-(piperazin-1-yl)isoindolin-2-yl)piperidine-2,6-dione hydrochloride

CAS Number

2242743-87-7

PubChem ID

146173390

InChI Key

CDDVRWUWIZZRJK-UHFFFAOYSA-N

SMILES

O=C1N(CC2=CC(N3CCNCC3)=CC(OC)=C12)C4C(NC(CC4)=O)=O.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Background References

References are publications that support the biological activity of the product.

Product Documents for Lenalidomide 5'-piperazine-7'-methoxy

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Lenalidomide 5'-piperazine-7'-methoxy

For research use only

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