Lenalidomide 5'-amine
Tocris Bioscience, part of Bio-Techne | Catalog # 7677
Cereblon ligand with terminal amine for onward chemistry
Key Product Details
Description
Cereblon ligand with terminal amine for onward chemistry
Product Description
Lenalidomide 5'-amine is a functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand with a terminal amine for onward chemistry to generate Protein Degraders with rigid linkers. Part of a range of functionalized tool molecules for PROTAC R&D.Please contact us for SD files of our available Degrader Building Blocks.
PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
Usage Guidelines
This product is provided for use in onward chemistry. Suitable solvents can be used.Product Specifications
Molecular Weight
259.27
Formula
C13H13N3O3
Storage
Store at -20°C
Purity
≥95% (HPLC)
Chemical Name
3-(5-Amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione
CAS Number
191732-70-4
PubChem ID
9816615
InChI Key
WLUIQUZGNPAKRL-UHFFFAOYSA-N
SMILES
NC1=CC2=C(C(N(C3CCC(NC3=O)=O)C2)=O)C=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Muller Amino-substituted thalidomide analogs: potent inhibitors of TNF-alpha production. Bioorg.Med.Chem.Lett. 1999 PMID: 10386948
Product Specific Notices for Lenalidomide 5'-amine
For research use only
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