Lenalidomide 5'-amine

Name: Lenalidomide 5'-amine
Brand: Tocris Bioscience
SKU: 7677

Tocris Bioscience, part of Bio-Techne | Catalog # 7677

COA / SDS

Cereblon ligand with terminal amine for onward chemistry

Key Product Details

Description:	Cereblon ligand with terminal amine for onward chemistry
Chemical Name:	3-(5-Amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione
Purity:	≥95% (HPLC)
Molecular Weight:	259.27

View Full Technical Details for Lenalidomide 5'-amine

Technical Data
Citations

Biological Activity for Lenalidomide 5'-amine

Lenalidomide 5'-amine is a functionalized cereblon ligand for PROTAC^® research and development; incorporates an E3 ligase ligand with a terminal amine for onward chemistry to generate Protein Degraders with rigid linkers. Part of a range of functionalized tool molecules for PROTAC R&D.

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC^® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Technical Data for Lenalidomide 5'-amine

M. Wt	259.27
Formula	C₁₃H₁₃N₃O₃
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	191732-70-4
PubChem ID	9816615
InChi Key	WLUIQUZGNPAKRL-UHFFFAOYSA-N
Smiles	NC1=CC2=C(C(N(C3CCC(NC3=O)=O)C2)=O)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Lenalidomide 5'-amine

References are publications that support the biological activity of the product.

Muller Amino-substituted thalidomide analogs: potent inhibitors of TNF-alpha production. Bioorg.Med.Chem.Lett. 1999 PMID: 10386948