L-NIO dihydrochloride
Tocris Bioscience, part of Bio-Techne | Catalog # 0546
NOS inhibitor
Product Description
L-NIO dihydrochloride is an Inhibitor of nitric oxide (NO) synthase. Inhibits iNOS, eNOS and nNOS. Active in vivo.Product Specifications
Molecular Weight
246.13
Formula
C7H15N3O2.2HCl
Storage
Store at -20°C
Chemical Name
N5-(1-Iminoethyl)-L-ornithine dihydrochloride
CAS Number
159190-44-0
PubChem ID
2733507
InChI Key
RYCMAAFECCXGHI-ILKKLZGPSA-N
SMILES
N[C@H](C(O)=O)CCCNC(C)=N.Cl.Cl
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 24.61 | 100 |
Preparing Stock Solutions
for L-NIO dihydrochloride
The following data is based on the product molecular weight 246.13
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 4.06 mL | 20.31 mL | 40.63 mL |
| 5 mM | 0.81 mL | 4.06 mL | 8.13 mL |
| 10 mM | 0.41 mL | 2.03 mL | 4.06 mL |
| 50 mM | 0.08 mL | 0.41 mL | 0.81 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Mulligan Protective effects of inhibitors of nitric oxide synthase in immune complex-induced vasculitis. Br.J.Pharmacol. 1992 PMID: 1281719
- Rees Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo. Br.J.Pharmacol. 1990 PMID: 1706208
- Moncada XIV. International Union of Pharmacology nomenclature in nitric oxide research. Pharmacol.Rev. 1997 PMID: 9228663
Product Specific Notices for L-NIO dihydrochloride
For research use only
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