L-745,870 trihydrochloride
Tocris Bioscience a Bio-Techne Brand
Key Product Details
Description: | Highly selective D4 antagonist |
Chemical Name: | 3-(4-[4-Chlorophenyl]piperazin-1-yl)-methyl-1H-pyrrolo[2,3-b]pyridine trihydrochloride |
Purity: | ≥99% (HPLC) |
Molecular Weight: | 436.21 |
Complete Your Research
Citations for L-745,870 trihydrochloride (13)
Citations are publications that use Bio-Techne products. Selected citations for L-745,870 trihydrochloride include:
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Sharma et al.
(2021)
Epithelial phenotype restoring drugs suppress macular degeneration phenotypes in an iPSC model.
Nat Commun.
12:7293
PMID: 34911940 -
Matsui and Alvarez
(2018)
Cocaine Inhibition of Synaptic Transmission in the Ventral Pallidum Is Pathway-Specific and Mediated by Serotonin.
Cell Rep.
23(13):3852
PMID: 29949769 -
Huang
(2017)
Neurochemical arguments for the use of DA D4 receptor stimulation to improve cognitive impairment associated with schizophrenia.
Pharmacol Biochem Behav.
157:16
PMID: 28455127 -
Guo
(2017)
DA D4 receptor activation restores CA1 LTP in hippocampal slices from aged mice.
Aging Cell.
16(6):1323
PMID: 28975698 -
Dai et al.
(2017)
Is DA transporter-mediated DArgic signaling in the retina a noninvasive biomarker for attention-deficit/ hyperactivity disorder? A study in a novel DA transporter variant Val559 transgenic mouse model.
J Neurodev Disord.
9:38
PMID: 29281965 -
Picton et al.
(2016)
Mechanisms underlying the endogenous DArgic inhibition of spinal locomotor circuit function in Xenopus tadpoles.
Scientific Reports.
6:35749
PMID: 27760989 -
Jensen
(2015)
Effects of DA D2-Like Receptor Antagonists on Light Responses of Ganglion Cells in Wild-Type and P23H Rat Retinas.
PLoS One.
10:e0146154
PMID: 26717015 -
Chen et al.
(2015)
Activation of D4 DA receptor decreases angiotensin II type 1 receptor expression in rat renal proximal tubule cells.
Autophagy.
65:153
PMID: 25368031 -
Suárez-Boomgaard et al.
(2014)
DA D4 receptor counteracts morphine-induced changes in � opioid receptor signaling in the striosomes of the rat caudate putamen.
Int J Mol Sci.
15:1481
PMID: 24451133 -
Steullet et al.
(2014)
Fast oscillatory activity in the anterior cingulate cortex: DArgic modulation and effect of perineuronal net loss.
Front Cell Neurosci.
8:244
PMID: 25191228 -
Herwerth et al.
(2012)
D4 DA receptors modulate NR2B NMDA receptors and LTP in stratum oriens of hippocampal CA1.
Cereb Cortex.
22:1786
PMID: 21955919 -
Okada et al.
(2005)
A DA D4 receptor antagonist attenuates ischemia-induced neuronal cell damage via upregulation of neuronal apoptosis inhibitory protein.
Hypertension.
25:794
PMID: 15729293 -
Basso et al.
(2005)
Antidepressant-like effect of D(2/3) receptor-, but not D(4) receptor-activation in the rat forced swim test.
Neuropsychopharmacology.
30:1257
PMID: 15688083
There are no citations that match your criteria.
Customer Reviews for L-745,870 trihydrochloride (1)
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Species: MouseAssay Type: In VivoL-745870 (100 nM)
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