Ketanserin tartrate
Tocris Bioscience a Bio-Techne Brand
Key Product Details
Description: | Selective 5-HT2A antagonist. Also antagonist at 5-HT1D |
Alternative Names: | R 41 468 |
Chemical Name: | 3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,4[1H,3H]-quinazolinedione tartrate |
Purity: | ≥97% (HPLC) |
Molecular Weight: | 545.52 |
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Citations for Ketanserin tartrate (22)
Citations are publications that use Bio-Techne products. Selected citations for Ketanserin tartrate include:
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Nguyen et al.
(2019)
Potentiation of the glycine response by serotonin on the substantia gelatinosa neurons of the trigeminal subnucleus caudalis in mice.
Korean J Physiol Pharmacol.
23:271
PMID: 31297011 -
Courtiol et al.
(2018)
Maternal Regulation of Pups' Cortical Activity: Role of Serotonergic Signaling.
Eneuro.
5
PMID: 30073196 -
Hirono
(2017)
Monoaminergic modulation of GABAergic transmission onto cerebellar globular cells.
Neuropharmacology.
118:79
PMID: 28300552 -
Medrihan et al.
(2017)
Initiation of Behavioral Response to Antidepressants by Cholecystokinin Neurons of the Dentate Gyrus.
Neuron.
95:564
PMID: 28735749 -
Fanarioti et al.
(2015)
Behavioral and neurochemical changes in mesostriatal DArgic regions of the rat after chronic administration of the cannabinoid receptor agonist WIN55,212-2.
Synapse.
18
PMID: 25522428 -
Kasper et al.
(2015)
Serotonin-2C receptor agonists decrease potassium-stimulated GABA release in the nucleus accumbens.
Neuropharmacology.
69:78
PMID: 25382408 -
Jiang et al.
(2015)
Potentiation of 5-methoxy-N,N-dimethyltryptamine-induced hyperthermia by harmaline and the involvement of activation of 5-HT1A and 5-HT2A receptors.
Br J Pharmacol.
89:342
PMID: 25446678 -
Kuo et al.
(2014)
A xanthine-derivative K(+)-channel opener protects against serotonin-induced cardiomyocyte hypertrophy via the modulation of protein kinases.
Int J Biol Sci.
10:64
PMID: 24391452 -
Saxena et al.
(2013)
Neuroprotection through excitability and mTOR required in ALS motoneurons to delay disease and extend survival.
Neuron.
80:80
PMID: 24094105 -
Ratner et al.
(2012)
Cerebral markers of the serotonergic system in rat models of obesity and after Roux-en-Y gastric bypass.
Neuron.
20:2133
PMID: 22450706 -
Morecroft et al.
(2012)
Gene therapy by targeted adenovirus-mediated knockdown of pulmonary endothelial Tph1 attenuates hypoxia-induced pulmonary hypertension.
Cereb Cortex.
20:1516
PMID: 22525513 -
Wood et al.
(2011)
Serotonin, via HTR2 receptors, excites neurons in a cortical-like premotor nucleus necessary for song learning and production.
J Neurosci.
31:13808
PMID: 21957243 -
Kleinbongard et al.
(2011)
Vasoconstrictor potential of coronary aspirate from patients undergoing stenting of saphenous vein aortocoronary bypass grafts and its pharmacological attenuation.
Circ Res.
108:344
PMID: 21183739 -
Johnson et al.
(2011)
Serotonin receptor activity is necessary for olfactory learning and memory in Drosophila melanogaster.
Neuroscience.
192:372
PMID: 21749913 -
Morecroft et al.
(2010)
In vivo effects of a combined 5-HT1B receptor/SERT antagonist in experimental pulmonary hypertension.
Int J Neuropsychopharmacol.
85:593
PMID: 19736308 -
Watakabe et al.
(2009)
Enriched expression of serotonin 1B and 2A receptor genes in macaque visual cortex and their bidirectional modulatory effects on neuronal responses.
Br J Pharmacol.
19:1915
PMID: 19056862 -
Huang et al.
(2009)
Repeated cocaine administration decreases 5-HT(2A) receptor-mediated serotonergic enhancement of synaptic activity in rat medial prefrontal cortex.
Neuropsychopharmacology.
34:1979
PMID: 19212317 -
Mbaki
(2008)
Investigation of the role of 5-HT2 receptor subtypes in the control of the bladder and the urethra in the anaesthetized female rat.
Br J Pharmacol.
155:343
PMID: 18604238 -
González-Maeso et al.
(2007)
Hallucinogens recruit specific cortical 5-HT(2A) receptor-mediated signaling pathways to affect behavior.
Mol Ther.
53:439
PMID: 17270739 -
Hampson et al.
(2007)
Stimulation of glycogen synthesis and inactivation of phosphorylase in hepatocytes by serotonergic mechanisms, and counter-regulation by atypical antipsychotic drugs.
Diabetologia.
50:1743
PMID: 17579833 -
Marinelli et al.
(2004)
Serotonergic and nonserotonergic dorsal raphe neurons are pharmacologically and electrophysiologically heterogeneous.
J Neurophysiol.
92:3532
PMID: 15254076 -
Morecroft et al.
(1999)
5-hydroxytryptamine receptors mediating contraction in human small muscular pulmonary arteries: importance of the 5-HT1B receptor.
Obesity (Silver Spring).
128:730
PMID: 10516655
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Customer Reviews for Ketanserin tartrate (1)
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Species: MouseAssay Type: In Vivo20mM ketanserin
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