JZL 195

Tocris Bioscience, part of Bio-Techne | Catalog # 4715

Dual FAAH and MAGL inhibitor
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Key Product Details

Description

Dual FAAH and MAGL inhibitor

View all Fatty Acid Amide Hydrolase (FAAH) Inhibitors »

Product Description

JZL 195 is a dual inhibitor of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) (IC50 values are 2 and 4 nM respectively). Elevates anandamide and 2-arachidonoylglycerol levels in vivo. Shown to impair short-term memory in mice.

Product Specifications

Molecular Weight

433.46

Formula

C24H23N3O5

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

4-[(3-Phenoxyphenyl)methyl]-1-piperazinecarboxylic acid 4-nitrophenyl ester

CAS Number

1210004-12-8

PubChem ID

46232606

InChI Key

QNYRAEKLMNDRFY-UHFFFAOYSA-N

SMILES

O=C(OC4=CC=C([N+]([O-])=O)C=C4)N(CC3)CCN3CC1=CC(OC2=CC=CC=C2)=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 21.67 50

Preparing Stock Solutions for JZL 195

The following data is based on the product molecular weight 433.46

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 4.61 mL 23.07 mL 46.14 mL
2.5 mM 0.92 mL 4.61 mL 9.23 mL
5 mM 0.46 mL 2.31 mL 4.61 mL
25 mM 0.09 mL 0.46 mL 0.92 mL

Calculators

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Product Documents for JZL 195

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for JZL 195

For research use only

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