JF-NP-26

Name: JF-NP-26
Brand: Tocris Bioscience
SKU: 6553

Tocris Bioscience, part of Bio-Techne | Catalog # 6553

COA / SDS

Caged Raseglurant (Cat. No. 4416)

Discontinued Product

6553 has been discontinued. View all Caged Compounds products.

Key Product Details

Description:	Caged Raseglurant (Cat. No. 4416)
Chemical Name:	(7-(Diethylamino)-2-oxo-2H-chromen-4-yl)methyl (2-((3-fluorophenyl)ethynyl)-4,6-dimethylpyridin-3-yl)carbamate
Purity:	≥98% (HPLC)
Molecular Weight:	513.56

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Technical Data
Citations

Biological Activity for JF-NP-26

JF-NP-26 is a caged Raseglurant (Cat. No. 4416). Releases raseglurant upon exposure to 405 nm (violet) light. Inhibits the effects of Quisqualate (Cat. No. 0188) in cultured neurons when exposed to 405 nm light. Exhibits analgesic activity in pain models in vivo on photoactivation. Quantum yield = 0.18.

Technical Data for JF-NP-26

M. Wt	513.56
Formula	C₃₀H₂₈FN₃O₄
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	2341841-03-8
Smiles	CC1=CC(C)=C(NC(OCC2=CC(OC3=C2C=CC(N(CC)CC)=C3)=O)=O)C(C#CC4=CC=CC(F)=C4)=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for JF-NP-26

References are publications that support the biological activity of the product.

Font Optical control of pain in vivo with a photoactive mGlu5 receptor negative allosteric modulator. eLIFE 2017 PMID: 28395733

JF-NP-26

Tocris Bioscience, part of Bio-Techne | Catalog # 6553

Key Product Details

Biological Activity for JF-NP-26

Technical Data for JF-NP-26

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for JF-NP-26

Product Documents for JF-NP-26

COA

Certificate of Analysis

SDS

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