Ifenprodil hemitartrate
Tocris Bioscience a Bio-Techne Brand
Key Product Details
Description: | Non-competitive NMDA antagonist; also σ ligand |
Chemical Name: | (1R*,2S*)-erythro-2-(4-Benzylpiperidino)-1-(4-hydroxyphenyl)-1-propanol hemi-(DL)-tartrate |
Purity: | ≥99% (HPLC) |
Molecular Weight: | 400.49 |
Complete Your Research
Citations for Ifenprodil hemitartrate (32)
Citations are publications that use Bio-Techne products. Selected citations for Ifenprodil hemitartrate include:
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Regan et al.
(2019)
Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors.
Nat Commun.
10:321
PMID: 30659174 -
McKay et al.
(2018)
The Developmental Shift of NMDA Receptor Composition Proceeds Independently of GluN2 Subunit-Specific GluN2 C-Terminal Sequences.
Cell Rep.
25:841
PMID: 30355491 -
Kashima and Grueter
(2017)
Toll-like receptor 4 deficiency alters nucleus accumbens synaptic physiology and drug reward behavior.
Proc Natl Acad Sci U S A..
114(33):8865
PMID: 28760987 -
Grochowska et al.
(2017)
Posttranslational modification impact on the mechanism by which amyloid-β induces synaptic dysfunction.
EMBO Rep.
18:962
PMID: 28420656 -
Galvez et al.
(2016)
Activation of α7 nicotinic acetylcholine receptors protects potentiated synapses from depotentiation during theta pattern stimulation in the hippocampal CA1 region of rats.
Neuropharmacology.
105:378
PMID: 26867505 -
Dolma et al.
(2016)
Inhibition of Dopamine Receptor D4 Impedes Autophagic Flux, Proliferation, and Survival of Glioblastoma Stem Cells.
Cancer Cell.
29:859
PMID: 27300435 -
Engelhardt et al.
(2015)
GluN2D-containing NMDA receptors-mediate synaptic currents in hippocampal interneurons and pyramidal cells in juvenile mice.
Proc Natl Acad Sci U S A.
9:95
PMID: 25859181 -
Simma et al.
(2014)
NMDA-receptor antagonists block B-cell function but foster IL-10 production in BCR/CD40-activated B cells.
Cell Commun Signal.
12:75
PMID: 25477292 -
Thomazeau et al.
(2014)
Prefrontal deficits in a murine model overexpressing the down syndrome candidate gene dyrk1a.
J Neurosci.
34:1138
PMID: 24453307 -
Mirante et al.
(2014)
Distinct molecular components for thalamic- and cortical-dependent plasticity in the lateral amygdala.
J Neurosci.
7:62
PMID: 25071439 -
Sánchez-Blázquez et al.
(2014)
The calcium-sensitive σ-1 receptor prevents cannabinoids from provoking glutamate NMDA receptor hypofunction: implications in antinociception and psychotic diseases.
Front Cell Neurosci.
17:1943
PMID: 24485144 -
Brady et al.
(2013)
Moderate prenatal alcohol exposure reduces plasticity and alters NMDA receptor subunit composition in the dentate gyrus.
Int J Neuropsychopharmacol.
33:1062
PMID: 23325244 -
Wills et al.
(2012)
GluN2B subunit deletion reveals key role in acute and chronic ethanol sensitivity of glutamate synapses in bed nucleus of the stria terminalis.
Proc Natl Acad Sci U S A.
109:E278
PMID: 22219357 -
Hedegaard et al.
(2012)
Molecular pharmacology of human NMDA receptors.
Neurochem Int.
61:601
PMID: 22197913 -
Heinrich et al.
(2012)
K+ depolarization evokes ATP, adenosine and glutamate release from glia in rat hippocampus: a microelectrode biosensor study.
Br J Pharmacol.
167:1003
PMID: 22394324 -
Gaamouch et al.
(2012)
Interaction between αCaMKII and GluN2B controls ERK-dependent plasticity.
J Neurosci.
32:10767
PMID: 22855824 -
Gourley et al.
(2012)
Arg kinase regulates prefrontal dendritic spine refinement and cocaine-induced plasticity.
J Neurosci.
32:2314
PMID: 22396406 -
McKay et al.
(2012)
Direct pharmacological monitoring of the developmental switch in NMDA receptor subunit composition using TCN 213, a GluN2A-selective, glycine-dependent antagonist.
Br J Pharmacol.
166:924
PMID: 22022974 -
Zhang and Sun
(2011)
Development of NMDA NR2 subunits and their roles in critical period maturation of neocortical GABAergic interneurons.
J Neurosci.
71:221
PMID: 20936660 -
Roselli et al.
(2011)
CDK5 is essential for soluble amyloid β-induced degradation of GKAP and remodeling of the synaptic actin cytoskeleton.
PLoS One.
6:e23097
PMID: 21829588 -
Higley and Sabatini
(2010)
Competitive regulation of synaptic Ca2+ influx by D2 DA and A2A adenosine receptors.
Nat Neurosci.
13:958
PMID: 20601948 -
Yuan et al.
(2009)
The serine protease plasmin cleaves the amino-terminal domain of the NR2A subunit to relieve zinc inhibition of the N-MthD.-aspartate receptors.
J Biol Chem.
284:12862
PMID: 19240037 -
Popp et al.
(2008)
Cerebellar granule cells cultured from adolescent rats express functional NMDA receptors: an in vitro model for studying the developing cerebellum.
J Neurochem.
106:900
PMID: 18466339 -
Fontaine et al.
(2008)
Vulnerability of white matter towards antenatal hypoxia is linked to a species-dependent regulation of glutamate receptor subunits.
Dev Neurobiol.
105:16779
PMID: 18922769 -
Nateri et al.
(2007)
ERK activation causes epilepsy by stimulating NMDA receptor activity.
EMBO J.
26:4891
PMID: 17972914 -
Ge et al.
(2007)
A critical period for enhanced synaptic plasticity in newly generated neurons of the adult brain.
Neuron.
54:559
PMID: 17521569 -
Logan et al.
(2007)
Long-lasting NMDA receptor-mediated EPSCs in mouse striatal medium spiny neurons.
J Neurophysiol.
98:2693
PMID: 17804581 -
Amadoro et al.
(2006)
NMDA receptor mediates tau-induced neurotoxicity by calpain and ERK/MAPK activation.
Proc Natl Acad Sci U S A.
103:2892
PMID: 16477009 -
Kopp et al.
(2006)
Insufficient sleep reversibly alters bidirectional synaptic plasticity and NMDA receptor function.
J Neurosci.
26:12456
PMID: 17135407 -
Shin et al.
(2005)
The dextromethorphan analog dimemorfan attenuates kainate-induced seizures via sigma1 receptor activation: comparison with the effects of dextromethorphan.
Br J Pharmacol.
144:908
PMID: 15723099 -
Yang et al.
(2005)
Behavioral stress enhances hippocampal CA1 long-term depression through the blockade of the glutamate uptake.
PLoS One.
25:4288
PMID: 15858055 -
Ning et al.
(2004)
Dual neuroprotective signaling mediated by downregulating two distinct phosphatase activities of PTEN.
J Neurosci.
24:4052
PMID: 15102920
There are no citations that match your criteria.